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Document and Entity Information - USD ($)	12 Months Ended
Document and Entity Information - USD ($)	Dec. 31, 2016	Mar. 20, 2017	Jun. 30, 2016
Document And Entity Information
Entity Registrant Name	Imprimis Pharmaceuticals, Inc.
Entity Central Index Key	0001360214
Document Type	10-K
Document Period End Date	Dec. 31, 2016
Amendment Flag	false
Current Fiscal Year End Date	--12-31
Entity Well-known Seasoned Issuer	No
Entity Voluntary Filer	No
Entity Current Reporting Status	Yes
Entity Filer Category	Smaller Reporting Company
Entity Public Float			$ 45,000,000
Entity Common Stock, Shares Outstanding		18,627,915
Trading Symbol	IMMY
Document Fiscal Period Focus	FY
Document Fiscal Year Focus	2016

Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Current assets
Cash and cash equivalents	$ 8,853	$ 2,685
Restricted cash and short-term investments	200	150
Accounts receivable, net	2,921	840
Inventories	1,841	1,412
Prepaid expenses and other current assets	938	786
Total current assets	14,753	5,873
Property, plant and equipment, net	7,295	2,657
Intangible assets, net	2,972	3,135
Goodwill	2,227	2,466
TOTAL ASSETS	27,247	14,131
Current liabilities
Accounts payable and accrued expenses	3,538	3,407
Accrued payroll and related liabilities	1,638	1,200
Deferred revenue and customer deposits	91	65
Current portion of deferred acquisition obligation and accrued interest	207	198
Current portion of contingent acquisition obligation		483
Current portion of note payable, net of unamortized debt discount	3,973
Current portion of capital lease obligations, net of unamortized discount	458	21
Total current liabilities	9,905	5,374
Capital lease obligations, net of current portion and unamortized discount	1,318	1
Deferred acquisition obligation, net of current portion	52	258
Accrued expenses, net of current portion	667	500
Deferred tax liability	936	1,047
Note payable and paid-in-kind interest, net of unamortized debt discount and current portion	7,937	8,336
TOTAL LIABILITIES	20,815	15,516
STOCKHOLDERS' EQUITY (DEFICIT)
Common stock, $0.001 par value, 90,000,000 shares authorized, 18,627,915 and 9,755,678 shares issued and outstanding at December 31, 2016 and 2015, respectively	19	10
Additional paid-in capital	83,264	56,369
Accumulated deficit	(76,851)	(57,764)
TOTAL STOCKHOLDERS' EQUITY (DEFICIT)	6,432	(1,385)
TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY (DEFICIT)	$ 27,247	$ 14,131

Consolidated Balance Sheets (Parenthetical) - $ / shares	Dec. 31, 2016	Dec. 31, 2015
Statement of Financial Position [Abstract]
Common stock, par value	$ 0.001	$ 0.001
Common stock, shares authorized	90,000,000	90,000,000
Common stock, shares issued	18,627,915	9,755,678
Common stock, shares outstanding	18,627,915	9,755,678

Consolidated Statements of Operations - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015
Revenues:
Sales, net	$ 19,927	$ 9,654
License revenues	15	62
Total revenues	19,942	9,716
Cost of sales	(9,831)	(5,206)
Gross profit	10,111	4,510
Operating expenses:
Selling and marketing	7,382	6,496
General and administrative	17,569	12,504
Research and development	739	332
Impairment of long-lived assets	303
Total operating expenses	25,993	19,332
Loss from operations	(15,882)	(14,822)
Other income (expense):
Interest expense, net	(2,774)	(1,108)
Early extinguishment of debt	(1,966)
Change in fair value of derivative liabilities	(113)
Other income, net	1,537	31
Income tax benefit (provision)	111
Total other expenses, net	(3,205)	(1,077)
Net loss	$ (19,087)	$ (15,899)
Basic and diluted net loss per share of common stock	$ (1.50)	$ (1.66)
Weighted average number of shares of common stock outstanding, basic and diluted	12,743,184	9,576,142

Consolidated Statements of Stockholders' Equity (Deficit) - USD ($) $ in Thousands	Common Stock [Member]	Additional Paid-in Capital [Member]	Accumulated Deficit [Member]	Total
Balance at Dec. 31, 2014	$ 9	$ 50,006	$ (41,865)	$ 8,150
Balance, share at Dec. 31, 2014	9,258,231
Exercise of stock options
Exercise of stock options, shares	130,457			130,457
Issuance of common stock upon vesting of RSUs net of tax withholding		(10)		$ (10)
Issuance of common stock upon vesting of RSUs net of tax withholding , shares	10,132
Sale of stock, net of offering costs (ATM)		404		404
Sale of stock, net of offering costs (ATM), shares	72,421
Exercise of warrants	$ 1	1,247		1,248
Exercise of warrants, shares	220,912
The Park Acquisition		425		425
The Park Acquisition, shares	63,525
Relative fair value of warrants to purchase common stock issued in connection with note payable		840		840
Relative fair value of warrants to purchase common stock issued in connection with note payable, shares
Stock-based compensation expense		3,457		3,457
Net loss			(15,899)	(15,899)
Balance at Dec. 31, 2015	$ 10	56,369	(57,764)	(1,385)
Balance, share at Dec. 31, 2015	9,755,678
Exercise of stock options		55		55
Exercise of stock options, shares	15,000
Issuance of common stock upon vesting of RSUs net of tax withholding	$ 1	(144)		(143)
Issuance of common stock upon vesting of RSUs net of tax withholding , shares	132,367
Sale of stock, net of offering costs (ATM)		212		212
Sale of stock, net of offering costs (ATM), shares	57,042
Stock-based compensation expense		3,811		3,811
Registered public offering sale of stock, net of offering costs, March 2016	$ 3	11,085		11,088
Registered public offering sale of stock, net of offering costs, March 2016, shares	3,335,000
Private placement, issuance of stock and warrants at $1.915 per unit, net of costs, in December 2016	$ 5	9,212		9,217
Private placement, issuance of stock and warrants at $1.915 per unit, net of costs, in December 2016, shares	5,257,828
Stock-based payment for deferred acquisition obligation		302		302
Stock-based payment for deferred acquisition obligation, shares	75,000
Derivative liabilities in connection with convertible note and modification of warrants to purchase common stock issued in connection with note payable		2,362		2,362
Derivative liabilities in connection with convertible note and modification of warrants to purchase common stock issued in connection with note payable, shares
Net loss			(19,087)	(19,087)
Balance at Dec. 31, 2016	$ 19	$ 83,264	$ (76,851)	$ 6,432
Balance, share at Dec. 31, 2016	18,627,915

Consolidated Statements of Stockholders' Equity (Deficit) (Parenthetical) - $ / shares	Dec. 31, 2016	Mar. 16, 2016
Statement of Stockholders' Equity [Abstract]
Issuance of stock and warrants price per share	$ 1.915	$ 3.60

Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015
CASH FLOWS FROM OPERATING ACTIVITIES
Net loss	$ (19,087)	$ (15,899)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization of furniture and equipment	1,055	255
Amortization of intangible assets	351	355
Amortization of deferred tax liability	(111)
Amortization of debt issuance costs and discount	970	281
Debt extinguishment	1,966
Paid-in-kind interest added to principal of note payable	203	130
Non-cash gain on contingent acquisition obligations	(83)	(31)
Change in fair value of derivative liabilities	113
Impairment of long-lived assets	303
Stock-based compensation	3,673	3,441
Issuance of warrant related to litigation settlement	115
Changes in assets and liabilities, net of effects from acquisitions:
Accounts receivable	(2,081)	(360)
Inventories	(429)	(314)
Prepaid expenses and other current assets	(152)	(545)
Accounts payable and accrued expenses	1,515	1,028
Accrued payroll and related liabilities	438	453
Deferred revenue and customer deposits	26	63
NET CASH USED IN OPERATING ACTIVITIES	(11,215)	(11,143)
CASH FLOWS FROM INVESTING ACTIVITIES
Purchase of Park Compounding, net of cash		(3,005)
Purchase of Central Allen Pharmacy, net of cash		(421)
Purchase of assets for ImprimisRx PA, Inc.		(524)
Payments on Pharmacy Creations contingent acquisition obligation	(100)
Investment in restricted marketable securities	(50)
Investment in patent and trademark assets	(252)	(185)
Purchases of property, plant and equipment	(6,887)	(995)
NET CASH USED IN INVESTING ACTIVITIES	(7,289)	(5,130)
CASH FLOWS FROM FINANCING ACTIVITIES
Payments on capital lease obligations	(267)	(25)
Net proceeds from public equity offering	11,088
Net proceeds from private placement equity offering	9,217
Payments on Park deferred acquisition obligation	(195)	(135)
Proceeds from note payable, net of issuance costs		9,265
Proceeds from convertible note payable, net of issuance costs	2,772
Proceeds from Essex leaseback, net of issuance costs	1,933
Net proceeds from ATM sales of common stock	212	404
Net proceeds (repurchases) from exercise of warrants and stock options, net of taxes remitted for RSU's	(88)	1,238
NET CASH PROVIDED BY FINANCING ACTIVITIES	24,672	10,747
NET CHANGE IN CASH AND CASH EQUIVALENTS	6,168	(5,526)
CASH AND CASH EQUIVALENTS, beginning of period	2,685	8,211
CASH AND CASH EQUIVALENTS, end of period	8,853	2,685
SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION:
Cash paid for income taxes	9	1
Cash paid for interest	1,366	637
SUPPLEMENTAL DISCLOSURES OF NON-CASH INVESTING AND FINANCING ACTIVITIES:
Fair value of embedded conversion feature recorded as debt discount and derivative liability	2,322
Reclassification of the fair value of the embedded conversion feature derivative liability to additional paid-in capital upon closing of the public equity offering	2,646
Reclassification of the fair value of the LSAF warrant from additional paid-in capital to derivative liability	675
Reclassification of the fair value of the LSAF warrant derivative liability to additional paid-in capital upon closing of the public equity offering	464
Reduction in value of warrant in connection with debt extinguishment	73
Issuance of common stock and fair value of deferred acquisition obligations related to the purchase of Park Compounding		1,016
Issuance of common stock and to settle contingent acquisition obligation related to the purchase of PC	302
Issuance of stock options for consulting services included in accounts payable and accrued expenses	23	39
Final fee on notes payable recorded as debt discount and included in accrued expenses		500
Estimated relative fair value of warrants issued in connection with note payable		840
Purchase of property, plant and equipment included in accounts payable and accrued expenses	$ 81	$ 1,275

Organization

12 Months Ended

Dec. 31, 2016

Organization, Consolidation and Presentation of Financial Statements [Abstract]

Organization

NOTE 1. ORGANIZATION

Imprimis Pharmaceuticals, Inc. (together with its subsidiaries, unless the context indicates or otherwise requires, the “Company” or “Imprimis”) is a pharmaceutical company dedicated to producing and dispensing high quality innovative medications in all 50 states. The Company’s unique business model increases patient access and affordability to many critical medicines. Headquartered in San Diego, California, Imprimis owns and operates three production and dispensing facilities located in California, New Jersey and Pennsylvania.

On April 1, 2014, the Company acquired Pharmacy Creations, LLC (“PC”), a New Jersey based compounding pharmacy and on January 1, 2015, the Company acquired South Coast Specialty Compounding, Inc. D/B/A Park Compounding (“Park”), a California based compounding pharmacy. Effective with the acquisition of PC, the Company commenced sales and marketing efforts for Imprimis’ portfolio of proprietary and non-proprietary compounded drug formulations. On August 4, 2015, the Company acquired JT Pharmacy, Inc. d/b/a Central Allen Pharmacy (“CAP”), a Texas based compounding pharmacy whose name has been changed to ImprimisRx TX, Inc. (See Note 18), and on October 15, 2015, the Company, through a wholly-owned subsidiary ImprimisRx PA, Inc. (“ImprimisRx PA”), acquired substantially all of the assets and tradenames of Thousand Oaks Holding Company’s wholly-owned subsidiaries Topical Apothecary Group, LLC (d/b/a TAG Pharmacy), Aerosol Science Laboratories, Inc. (d/b/a ASL Pharmacy), SinuTopic, Inc. (d/b/a Sinus Dynamics Pharmacy) and Mycotoxins, LLC (collectively “TOHC”).

Summary of Significant Accounting Policies

12 Months Ended

Dec. 31, 2016

Accounting Policies [Abstract]

Summary of Significant Accounting Policies

NOTE 2. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

Basis of Presentation

Imprimis has prepared the accompanying consolidated financial statements in accordance with accounting principles generally accepted in the United States of America (“GAAP”). The accompanying consolidated financial statements include the accounts of the Company and its wholly-owned subsidiaries. All intercompany accounts and transactions have been eliminated in consolidation.

Use of Estimates

The preparation of financial statements in conformity with GAAP requires management to make estimates and judgments that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and reported amounts of revenues and expenses during the reporting periods. Significant estimates made by management are, among others, allowance for doubtful accounts and contractual adjustments, realizability of inventories, valuation of deferred taxes, goodwill and intangible assets, recoverability of long-lived assets and goodwill, valuation of contingent acquisition obligations and deferred acquisition obligations, valuation of notes payable and derivative liabilities, and valuation of stock-based transactions with employees and non-employees. Actual results could differ from those estimates.

Liquidity

The Company has incurred significant operating losses and negative cash flows from operations since its inception. The Company incurred net losses of $19,087 and $15,899 for the years ended December 31, 2016 and 2015, respectively, and had an accumulated deficit of $76,851 and $57,764 as of December 31, 2016 and 2015, respectively. In addition, the Company used cash in operating activities of $11,215 and $11,143 for the years ended December 31, 2016 and 2015, respectively.

While there is no assurance, the Company believes its existing cash resources and restricted cash of approximately $9,053 at December 31, 2016, will be sufficient to sustain the Company’s planned level of operations for at least the next twelve months. However, estimates of operating expenses and working capital requirements could be incorrect, and the Company could use its cash resources faster than anticipated. Further, some or all of the ongoing or planned activities may not be successful and could result in further losses.

The Company may seek to increase liquidity and capital resources by one or more measures, to the extent necessary. These measures may include, but are not limited to, the following: obtaining financing through the issuance of equity, debt, or convertible securities; and working to increase revenue growth through pharmacy sales. There is no guarantee that the Company will be able to obtain capital when needed on terms it deems as acceptable, or at all.

Revenue Recognition and Deferred Revenue

The Company recognizes revenues when all of the following criteria have been met: (1) persuasive evidence of an arrangement exists; (2) delivery has occurred; (3) the selling price is fixed and determinable; and (4) collectability is reasonably assured.

Product Revenues

Determination of criteria (3) and (4) is based on management’s judgments regarding the fixed nature of the selling prices of the products delivered and the collectability of those amounts. Estimated returns and allowances and other adjustments are provided for in the same period during which the related sales are recorded. The Company will defer any revenues received for a product that has not been delivered or is subject to refund until such time that the Company and the customer jointly determine that the product has been delivered and no refund will be required.

License Revenues

License arrangements may consist of non-refundable upfront license fees, data transfer fees, research reimbursement payments, exclusive license rights to patented or patent pending compounds, technology access fees, and various performance or sales milestones. These arrangements can be multiple element arrangements.

Non-refundable fees that are not contingent on any future performance by the Company and require no consequential continuing involvement on the part of the Company are recognized as revenue when the license term commences and the licensed data, technology, compounded drug preparation and/or other deliverable is delivered. Such deliverables may include physical quantities of compounded drug preparations, design of the compounded drug preparations and structure-activity relationships, the conceptual framework and mechanism of action, and rights to the patents or patent applications for such compounded drug preparations. The Company defers recognition of non-refundable fees if it has continuing performance obligations without which the technology, right, product or service conveyed in conjunction with the non-refundable fee has no utility to the licensee and that are separate and independent of the Company’s performance under the other elements of the arrangement. In addition, if the Company’s continued involvement is required, through research and development services that are related to its proprietary know-how and expertise of the delivered technology or can only be performed by the Company, then such non-refundable fees are deferred and recognized over the period of continuing involvement. Guaranteed minimum annual royalties are recognized on a straight-line basis over the applicable term.

Cost of Sales

Cost of sales includes direct and indirect costs to manufacture formulations and other products sold, including active pharmaceutical ingredients, personnel costs, packaging, storage, royalties (see Note 16), shipping and handling costs and the write-off of obsolete inventory.

Research and Development

The Company expenses all costs related to research and development as they are incurred. Research and development expenses consist of expenses incurred in performing research and development activities, including salaries and benefits, other overhead expenses, and costs related to clinical trials, contract services and outsourced contracts.

Debt Issuance Costs and Debt Discount

Debt issuance costs and the debt discount are recorded net of notes payable and capital lease obligations in the consolidated balance sheets. Amortization expense of debt issuance costs and the debt discount is calculated using the effective interest method over the term of the debt and is recorded in interest expense in the accompanying consolidated statements of operations.

Intellectual Property

The costs of acquiring intellectual property rights to be used in the research and development process, including licensing fees and milestone payments, are charged to research and development expense as incurred in situations where the Company has not identified an alternative future use for the acquired rights, and are capitalized in situations where we have identified an alternative future use for the acquired rights. Patents and trademarks are recorded at cost and capitalized at a time when the future economic benefits of such patents and trademarks become more certain (see Goodwill and Intangible Assets). The Company began capitalizing certain costs associated with acquiring intellectual property rights during 2015, if costs are not capitalized they are expensed as incurred.

Income Taxes

As part of the process of preparing the Company’s consolidated financial statements, the Company must estimate the actual current tax liabilities and assess temporary differences resulting from differing treatment of items for tax and accounting purposes. These differences result in deferred tax assets and liabilities, which are included within the balance sheet. The Company must assess the likelihood that the deferred tax assets will be recovered from future taxable income and, to the extent the Company believes that recovery is not likely, a valuation allowance must be established. To the extent the Company establishes a valuation allowance or increase or decrease this allowance in a period, the impact will be included in income tax expense in the consolidated statement of operations.

The Company accounts for income taxes under the provisions of Financial Accounting Standards Board (the “FASB”) Accounting Standards Codification (“ASC”) 740, “Income Taxes”, or ASC 740. As of December 31, 2016 and 2015, there were no unrecognized tax benefits included in the consolidated balance sheets that would, if recognized, affect the effective tax rate. The Company’s practice is to recognize interest and/or penalties related to income tax matters in income tax expense. The Company had no accrual for interest or penalties in its consolidated balance sheets at December 31, 2016 and 2015, and has not recognized interest and/or penalties in the consolidated statements of operations for the years ended December 31, 2016 and 2015. The Company is subject to taxation in the United States, California, New Jersey, Texas and Pennsylvania. The Company’s tax years since 2000 are subject to examination by the federal and state tax authorities due to the carryforward of unutilized net operating losses.

Cash and Cash Equivalents

Cash equivalents include short-term, highly liquid investments with maturities of three months or less at the time of acquisition.

Concentrations of Credit Risk

The Company places its cash with financial institutions deemed by management to be of high credit quality. The Federal Deposit Insurance Corporation (“FDIC”) provides basic deposit coverage with limits up to $250 per owner. At December 31, 2016, the Company had approximately $8,800 in cash deposits in excess of FDIC limits.

Accounts Receivable

Accounts receivable are stated net of allowances for doubtful accounts and contractual adjustments. The accounts receivable balance primarily includes amounts due from customers the Company has invoiced or from third-party providers (e.g., insurance companies and governmental agencies), but for which payment has not been received. Charges to bad debt are based on both historical write-offs and specifically identified receivables. Contractual adjustments are determined by the amount expected to be collected from third-party providers. Accounts receivable are presented net of allowances for doubtful accounts and contractual adjustments in the amount of $422 and $180 as of December 31, 2016 and 2015, respectively.

Inventories

Inventories are stated at the lower of cost or market. Cost is determined on a first-in, first-out basis. The Company evaluates the carrying value of inventories on a regular basis, based on the price expected to be obtained for products in their respective markets compared with historical cost. Write-downs of inventories are considered to be permanent reductions in the cost basis of inventories.

The Company also regularly evaluates its inventories for excess quantities and obsolescence (expiration), taking into account such factors as historical and anticipated future sales or use in production compared to quantities on hand and the remaining shelf life of products and active pharmaceutical ingredients on hand. The Company establishes reserves for excess and obsolete inventories as required based on its analyses.

Property, Plant and Equipment

Property, plant and equipment is stated at cost less accumulated depreciation and amortization. Depreciation and amortization is calculated using the straight-line method over the estimated useful life of the asset. Leasehold improvements and capital lease equipment are amortized over the estimated useful life or remaining lease term, whichever is shorter. Computer software and hardware and furniture and equipment are depreciated over three to five years.

Business Combinations

The Company accounts for business combinations by recognizing the assets acquired, liabilities assumed, contractual contingencies, and contingent consideration at their fair values on the acquisition date. The purchase price allocation process requires management to make significant estimates and assumptions, especially with respect to intangible assets, estimated contingent consideration payments and pre-acquisition contingencies. Examples of critical estimates in valuing certain of the intangible assets the Company has acquired or may acquire in the future include but are not limited to:

	●	future expected cash flows from product sales, support agreements, consulting contracts, other customer contracts, and acquired developed technologies and patents; and

	●	discount rates utilized in valuation estimates.

Unanticipated events and circumstances may occur that may affect the accuracy or validity of such assumptions, estimates or actual results. Additionally, any change in the fair value of the acquisition-related contingent consideration subsequent to the acquisition date, including changes from events after the acquisition date, such as changes in our estimates of relevant revenue or other targets, will be recognized in earnings in the period of the estimated fair value change. A change in fair value of the acquisition-related contingent consideration or the occurrence of events that cause results to differ from our estimates or assumptions could have a material effect on the consolidated financial position, statements of operations or cash flows in the period of the change in the estimate.

Goodwill and Intangible Assets

Patents and trademarks are recorded at cost and capitalized at a time when the future economic benefits of such patents and trademarks become more certain. At that time, the Company capitalizes third-party legal costs and filing fees associated with obtaining and prosecuting claims related to its patents and trademarks. Once the patents have been issued, the Company amortizes these costs over the shorter of the legal life of the patent or its estimated economic life, generally 20 years, using the straight-line method. Trademarks are an indefinite life intangible asset and are assessed for impairment based on future projected cash flows as further described below.

The Company reviews its goodwill and indefinite-lived intangible assets for impairment as of January 1 of each year and when an event or a change in circumstances indicates the fair value of a reporting unit may be below its carrying amount. Events or changes in circumstances considered as impairment indicators include but are not limited to the following:

	●	significant underperformance of the Company’s business relative to expected operating results;

	●	significant adverse economic and industry trends;

	●	significant decline in the Company’s market capitalization for an extended period of time relative to net book value; and

	●	expectations that a reporting unit will be sold or otherwise disposed.

The goodwill impairment test consists of a two-step process as follows:

Step 1. The Company compares the fair value of each reporting unit to its carrying amount, including the existing goodwill. The fair value of each reporting unit is determined using a discounted cash flow valuation analysis. The carrying amount of each reporting unit is determined by specifically identifying and allocating the assets and liabilities to each reporting unit based on headcount, relative revenues or other methods as deemed appropriate by management. If the carrying amount of a reporting unit exceeds its fair value, an indication exists that the reporting unit’s goodwill may be impaired and the Company then performs the second step of the impairment test. If the fair value of a reporting unit exceeds its carrying amount, no further analysis is required.

Step 2. If further analysis is required, the Company compares the implied fair value of the reporting unit’s goodwill, determined by allocating the reporting unit’s fair value to all of its assets and its liabilities in a manner similar to a purchase price allocation, to its carrying amount. If the carrying amount of the reporting unit’s goodwill exceeds its fair value, an impairment loss will be recognized in an amount equal to the excess.

Impairment of Long-Lived Assets

Long-lived assets, such as property, plant and equipment, purchased intangibles subject to amortization and patents and trademarks, are reviewed for impairment whenever events or changes in circumstances indicate that the carrying amount of an asset may not be recoverable. Recoverability of assets to be held and used is measured by a comparison of the carrying amount of an asset to estimated undiscounted future cash flows expected to be generated by the asset. If the carrying amount of an asset exceeds its estimated future cash flows, an impairment charge is recognized in the amount by which the carrying amount of the asset exceeds the fair value of the asset. Assets to be disposed of would be separately presented in the consolidated balance sheet and reported at the lower of the carrying amount or fair value less costs to sell, and are no longer depreciated. The assets and liabilities of a disposal group classified as held-for-sale would be presented separately in the appropriate asset and liability sections of the consolidated balance sheet, if material.

In September 2016, the Company decided to cease operations at its Texas facility, and began winding down the operations. Based on current projections regarding future cash flows of the Texas facility and the related subsidiary, the evaluation resulted in an impairment of $64 related to intangible assets and $239 related to goodwill, recorded to impairment of long-lived assets on the consolidated statements of operations during the year ended December 31, 2016. During the year ended December 31, 2015, the Company did not recognize any impairment of its long-lived assets (See Note 18).

Third Party Billing and Collection Agreements

In connection with its acquisition of Park, the Company entered into a billing and collection agreement with a third party to assist in the billing and collection of workers’ compensation claims. Under the terms of the agreement, the Company is obligated to pay a fixed fee to the third party equal to 55% of the amounts billed and collected under the workers’ compensation claims. The Company accrues for such fees in accounts payable and accrued expenses in the accompanying consolidated balance sheets. Total billing and collection management expense under this agreement for the years ended December 31, 2016 and 2015 was $55 and $142, respectively, and is included in selling and marketing expenses in the accompanying consolidated statements of operations. The amount due under the agreement as of December 31, 2016 and 2015 was $73 and $81, respectively.

Deferred Rent

The Company accounts for rent expense related to its operating leases by determining total minimum rent payments on the leases over their respective periods and recognizing the rent expense on a straight-line basis. The difference between the actual amount paid and the amount recorded as rent expense in each fiscal year and interim periods within each fiscal year is recorded as an adjustment to deferred rent (See Note 9).

Fair Value Measurements

Fair value measurements are determined based on the assumptions that market participants would use in pricing an asset or liability. GAAP establishes a hierarchy for inputs used in measuring fair value that maximizes the use of observable inputs and minimizes the use of unobservable inputs by requiring that the most observable inputs be used when available. The established fair value hierarchy prioritizes the use of inputs used in valuation methodologies into the following three levels:

●	Level 1: Applies to assets or liabilities for which there are quoted prices (unadjusted) for identical assets or liabilities in active markets. A quoted price in an active market provides the most reliable evidence of fair value and must be used to measure fair value whenever available.

●	Level 2: Applies to assets or liabilities for which there are significant other observable inputs other than Level 1 prices, such as quoted prices for similar assets or liabilities; quoted prices in markets that are not active; or other inputs that are observable or can be corroborated by observable market data.

●	Level 3: Applies to assets or liabilities for which there are significant unobservable inputs that reflect a reporting entity’s own assumptions about the assumptions that market participants would use in pricing an asset or liability. For example, Level 3 inputs would relate to forecasts of future earnings and cash flows used in a discounted future cash flows method.

At December 31, 2016 and 2015, the Company did not have any financial assets or liabilities that are measured on a recurring basis. The Company’s financial instruments included cash and cash equivalents, restricted short-term investments, accounts receivable, accounts payable and accrued expenses, accrued payroll and related liabilities, deferred revenue and customer deposits, deferred acquisition obligations, notes payable and capital leases. The carrying amount of these financial instruments, except for deferred acquisition obligations, notes payable and capital leases, approximates fair value due to the short-term maturities of these instruments. The Company’s restricted short-term investments are carried at amortized cost, which approximates fair value. Based on borrowing rates currently available to the Company, the carrying values of the deferred acquisition obligations, notes payable and capital leases, approximate their respective fair values.

Derivative Instruments

The Company accounts for free-standing derivative instruments and hybrid instruments that contain embedded derivative features as either assets or liabilities in the consolidated balance sheets and are measured at fair value with gains or losses recognized in earnings. Embedded derivatives that are not clearly and closely related to the host contract are bifurcated and are recognized at fair value with changes in fair value recognized as either a gain or loss in earnings. The Company determines the fair value of derivative instruments and hybrid instruments based on available market data using appropriate valuation models, giving consideration to all of the rights and obligations of each instrument.

The Company estimates the fair value of derivative instruments and hybrid instruments using various techniques (and combinations thereof) that are considered to be consistent with the objective of measuring fair value. In selecting the appropriate technique, the Company considers, among other factors, the nature of the instrument, the market risks that it embodies and the expected means of settlement. The Company generally uses the Black-Scholes-Merton option pricing model, adjusted for the effect of dilution, because it embodies all of the requisite assumptions (including trading volatility, estimated terms, dilution and risk-free rates) necessary to fair value these instruments. Estimating the fair value of derivative financial instruments requires the development of significant and subjective estimates that may, and are likely to, change over the duration of the instrument with related changes in internal and external market factors. Increases in the trading price of the Company’s common stock and increases in fair value during a given financial quarter result in the application of non-cash derivative expense. Conversely, decreases in the trading price of the Company’s common stock and decreases in fair value during a given financial quarter would result in the application of non-cash derivative income.

Stock-Based Compensation

All stock-based payments to employees, directors and consultants, including grants of stock options, warrants, restricted stock units (“RSUs”) and restricted stock, are recognized in the consolidated financial statements based upon their estimated fair values. The Company uses the Black-Scholes-Merton option pricing model and Monte Carlo Simulation to estimate the fair value of stock-based awards. The estimated fair value is determined at the date of grant. The financial statement effect of forfeitures is estimated at the time of grant and revised, if necessary, if the actual effect differs from those estimates.

The Company’s accounting policy for equity instruments issued to consultants and vendors in exchange for goods and services follows FASB guidance. As such, the value of the applicable stock-based compensation is periodically remeasured and income or expense is recognized during the vesting terms of the equity instruments. The measurement date for the estimated fair value of the equity instruments issued is the earlier of (i) the date at which a commitment for performance by the consultant or vendor is reached or (ii) the date at which the consultant or vendor’s performance is complete. In the case of equity instruments issued to consultants, the estimated fair value of the equity instrument is primarily recognized over the term of the consulting agreement. According to FASB guidance, an asset acquired in exchange for the issuance of fully vested, nonforfeitable equity instruments should not be presented or classified as an offset to equity on the grantor’s balance sheet once the equity instrument is granted for accounting purposes. Accordingly, the Company records the estimated fair value of nonforfeitable equity instruments issued for future consulting services as prepaid stock-based consulting expenses in its consolidated balance sheets.

Basic and Diluted Net Loss per Common Share

Basic net loss per common share is computed by dividing net loss attributable to common stockholders for the period by the weighted average number of common shares outstanding during the period. Diluted net loss per share is computed by dividing the net loss attributable to common stockholders for the period by the weighted average number of common and common equivalent shares, such as stock options and warrants, outstanding during the period.

Basic and diluted net loss per share is computed using the weighted average number of shares of common stock outstanding during the period. Common stock equivalents (using the treasury stock and “if converted” method) from deferred acquisition obligations, stock options, unvested RSUs, warrants and convertible notes were 9,162,259 and 3,313,169 at December 31, 2016 and 2015, respectively, and are excluded from the calculation of diluted net loss per share for all periods presented because the effect is anti-dilutive. Included in the basic and diluted net loss per share calculation were RSUs awarded to directors that had vested, but the issuance and delivery of the shares are deferred until the director resigns. The number of shares underlying these vested RSUs at December 31, 2016 and 2015 was 80,245 and 55,824, respectively,

The following table shows the computation of basic and diluted net loss per share of common stock for the years ended December 31, 2016 and 2015:

	For the			For the
	Year Ended			Year Ended
	December 31, 2016			December 30, 2015

Numerator – net loss	$	(19,087	)	$	(15,899	)
Denominator – weighted average number of shares outstanding, basic and diluted		12,743,184			9,576,142
Net loss per share, basic and diluted	$	(1.50	)	$	(1.66	)

Recently Adopted Accounting Pronouncements

In August 2014, the FASB issued new accounting guidance which defines management’s responsibility to assess an entity’s ability to continue as a going concern, and to provide related footnote disclosures in certain circumstances. This guidance is effective for annual periods ended after December 15, 2016 and interim periods within annual periods beginning after December 15, 2016. Early adoption is permitted for annual or interim reporting periods for which the financial statements have not previously been issued. The Company has applied the guidance and disclosure provisions of the new standard upon adoption in its 2016 annual consolidated financial statements. The adoption of the guidance did not have a material impact on the Company’s consolidated financial statements and its related footnote disclosures.

Recently Issued Accounting Pronouncements

In May 2014, the FASB issued Accounting Standards Update (“ASU”) 2014-09, Revenue from Contracts with Customers. This updated guidance supersedes the current revenue recognition guidance, including industry-specific guidance. The updated guidance introduces a five-step model to achieve its core principal of the entity recognizing revenue to depict the transfer of goods or services to customers at an amount that reflects the consideration to which the entity expects to be entitled in exchange for those goods or services. The updated guidance is effective for interim and annual periods beginning after December 15, 2016, and early adoption is not permitted. In July 2015, the FASB decided to delay the effective date of ASU 2014-09 until December 15, 2017. The FASB also agreed to allow entities to choose to adopt the standard as of the original effective date. The Company is currently evaluating which transition method it will adopt and the expected impact of the updated guidance, but does not believe the adoption of the updated guidance will have a significant impact on its consolidated financial statements.

In February 2016, the FASB issued ASU 2016-02, Leases, which requires the lease rights and obligations arising from lease contracts, including existing and new arrangements, with terms more than 12 months to be recognized as assets and liabilities on the balance sheet. Recognition, measurement and presentation of expenses will depend on classification as a finance or operating lease. The amendments also require certain quantitative and qualitative disclosures about leasing arrangements. ASU 2016-02 is effective for reporting periods beginning after December 15, 2018 with early adoption permitted. While the Company is still evaluating ASU 2016-02, the Company expects the adoption of ASU 2016-02 to have a material effect on the Company’s consolidated financial condition due to the recognition of the lease rights and obligations as assets and liabilities. The Company does not expect ASU 2016-02 to have a material effect on the Company’s results of operations and cash flows.

In January 2016, the FASB issued ASU 2016-01, Financial Instruments: Recognition and Measurement of Financial Assets and Financial Liabilities, which addresses certain aspects of recognition, measurement, presentation and disclosure of financial statements. This guidance will be effective in the first quarter of fiscal year 2019 and early adoption is not permitted. The Company is currently evaluating the impact that this guidance will have on its consolidated financial statements.

In March 2016, the FASB issued ASU 2016-09, Compensation-Stock Compensation (Topic 718): Improvements to Employee Share-Based Payment Accounting, which addresses certain aspects of accounting for share-based payment award transactions. This guidance will be effective in the first quarter of fiscal year 2017 and early adoption is permitted. The Company is currently evaluating the impact that this guidance will have on its consolidated financial statements.

In July 2015, the FASB issued ASU 2015-11, Simplifying the Measurement of Inventory, which requires entities to measure most inventory “at the lower of cost and net realizable value (“NRV”),” thereby simplifying the current guidance under which an entity must measure inventory at the lower of cost or market. Under the new guidance, inventory is “measured at the lower of cost and net realizable value,” which eliminates the need to determine replacement cost and evaluate whether it is above the ceiling (NRV) or below the floor (NRV less a normal profit margin). The guidance defines NRV as the “estimated selling prices in the ordinary course of business, less reasonably predictable costs of completion, disposal, and transportation.” The guidance is effective for annual periods beginning after December 15, 2016, and interim periods therein. Early application is permitted. The Company is evaluating the impact of adoption of this guidance on its financial position and results of operations.

Acquisitions

12 Months Ended

Dec. 31, 2016

Business Combinations [Abstract]

Acquisitions

NOTE 3. ACQUISITIONS

Acquisition of Park

On January 1, 2015, the Company acquired all of the outstanding capital stock of Park (the “Park Acquisition”) from its previous owners (the “Sellers”), such that Park became a wholly owned subsidiary of the Company. The acquisition of Park permits the Company to make and distribute its patent-pending proprietary drug formulations and other novel pharmaceutical solutions through Park and introduces the Company to new geographic and compounded formulation markets.

The transaction has been accounted for as a business combination and the financial results of Park have been included in the Company’s consolidated financial statements for the period subsequent to the acquisition.

The estimated acquisition date fair value of consideration transferred, assets acquired and liabilities assumed for Park are presented below and represent the Company’s best estimates.

Fair Value of Consideration Transferred

At the closing of the Park Acquisition, the Company paid to the Sellers an aggregate cash purchase price of $3,000, net of fees and expenses, and a $100 payment for cash remaining in a Park bank account, and the Company issued to the Sellers 63,525 shares of the Company’s restricted common stock, valued at $500 based on the average closing price of the Company’s common stock for the 10 trading days preceding the closing. In addition, the Company is obligated to make 12 quarterly cash payments to the Sellers collectively of $53 each over the three years following the closing of the Park Acquisition, totaling $638; provided that the Sellers will have the option to receive the last six of such payments, totaling up to an aggregate of $319, in the form of 6,749 shares of the Company’s common stock for each such payment. The convertible features of the deferred consideration provide for a rate of conversion that is at market value, and as a result no value was attributed to the conversion feature. The Company also recorded a deferred tax liability of $1,047 related to the Park acquisition.

Management applied a discount rate of 15% to the restricted common stock issued at the closing of the Park Acquisition due to a lack of marketability of such shares as a result of certain restrictions on their transfer. The total acquisition date fair value of the consideration transferred and to be transferred is estimated at approximately $5,163.

A $591 liability was recognized for the estimated acquisition date fair value of the deferred consideration and is included in the deferred acquisition obligations in the accompanying consolidated balance sheet at December 31, 2015.

The total acquisition date fair value of consideration transferred and to be transferred is estimated as follows:

Cash payment to Sellers at closing	$	3,100
Restricted common stock issuance to Sellers at closing		425
Deferred tax liability		1,047
Deferred consideration to Sellers		591
Total acquisition date fair value	$	5,163

Allocation of Consideration Transferred

The identifiable assets acquired and liabilities assumed were recognized and measured as of the acquisition date based on their estimated fair values as of January 1, 2015, the acquisition date. The excess of the acquisition date fair value of consideration transferred over the estimated fair value of the net tangible assets and intangible assets acquired was recorded as goodwill.

The following table summarizes the estimated fair values of the assets acquired and liabilities assumed at the acquisition date.

Cash and cash equivalents	$	95
Accounts receivable		399
Inventories		232
Furniture and equipment		252
Intangible assets		2,629
Total identifiable assets acquired		3,607
Accounts payable and accrued expenses		304
Other liabilities		35
Total liabilities assumed		339
Total identifiable assets less liabilities assumed		3,268
Goodwill		1,895
Net assets acquired	$	5,163

During the year ended December 31, 2015 the discount rate of the common stock issued at the time of the Park Acquisition was adjusted from 25% to 15% which resulted in an increase of $46 and $4 in goodwill and intangible assets, respectively, compared to the initial allocation of the purchase price. The final allocation was based on estimates and appraisals that was based on the Company’s final evaluation of Park’s assets and liabilities, including both tangible and intangible assets.

Results of Operations

The amount of revenues and net income of Park included in the Company’s consolidated statement of operations from the acquisition date through the period ended December 31, 2015 are as follows:

Total revenues		$	6,134
Net income		$	1,088

Intangible Assets

Management engaged a third-party valuation firm to assist in the determination of the fair value of the acquired intangible assets of Park. In determining the fair value of the intangible assets, the Company considered, among other factors, the best use of the acquired assets, analyses of historical financial performance of Park and estimates of future performance of Park. The fair values of the identified intangible assets related to Park’s customer relationships, trade name, non-competition clause, and state pharmacy licenses. Customer relationships and the non-competition clause were calculated using the income approach. Trade name and state pharmacy licenses were calculated using the cost approach. The following table sets forth the components of identified intangible assets associated with the Park Acquisition and their estimated useful lives.

	Fair Value		Useful Life
Customer relationships	$	2,387		3 - 15 years
Trade name		10		5 years
Non-competition clause		224		3 years
State pharmacy licenses		8		25 years
	$	2,629

The Company determined the useful lives of intangible assets based on the expected future cash flows and contractual life associated with the respective assets. Trade name represents the fair value of the brand and name recognition associated with the marketing of Park’s formulations and services. Customer relationships represent the expected future benefit from contracts and relationships which, at the date of acquisition, were reasonably anticipated to continue given the history and operating practices of Park. The non-competition clause represents the contractual period and expected degree of adverse economic impact that would exist in its absence. Licenses represent twelve state pharmacy licenses Park held at the date of acquisition.

Goodwill

Of the total estimated purchase price for the Park Acquisition, $1,895 was allocated to goodwill and is attributable to expected synergies between the combined companies, including access for the Company to fulfill prescriptions with its patent-pending proprietary drug formulations through Park’s market channels and assembled workforce. Goodwill represents the excess of the purchase price of the acquired business over the fair value of the underlying net tangible and intangible assets acquired. Goodwill resulting from the business will be tested for impairment at least annually and more frequently if certain indicators are present. In the event the Company determines that the value of goodwill has become impaired, it will incur an accounting charge for the amount of the impairment during the fiscal quarter in which the determination is made. None of the goodwill is expected to be deductible for income tax purposes.

Other 2015 Acquisitions

During 2015, the Company acquired CAP and purchased the assets of TOHC, primarily to expand its compounding pharmacy infrastructure and offerings. These acquisitions were not individually significant. The Company has included the financial results of the CAP acquisition in its consolidated financial statements from its acquisition date and the results from this company were not individually material to the Company’s consolidated financial statements. The purchase price for these acquisitions totaled, collectively, approximately $945, which was paid entirely in cash. The Company recorded $641 of net tangible assets and $65 of identifiable intangible assets, based on their estimated fair values, and $239 of residual goodwill.

The acquisition of CAP was not individually significant and the 2015 results from this company were not individually material to our consolidated financial statements.

The Company incurred approximately $201 in acquisition expenses related to the Park Acquisition, $135 in expenses related to the acquisition of the assets of TOHC and did not incur material acquisition expenses related to the acquisition of CAP.

- Definition

The entire disclosure for a business combination (or series of individually immaterial business combinations) completed during the period, including background, timing, and recognized assets and liabilities. The disclosure may include leverage buyout transactions (as applicable).

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
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Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 805
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-Section 50
-Paragraph 4
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Reference 3: http://www.xbrl.org/2003/role/presentationRef
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-Name Accounting Standards Codification
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Reference 4: http://www.xbrl.org/2003/role/presentationRef
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Reference 5: http://www.xbrl.org/2003/role/presentationRef
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Reference 6: http://www.xbrl.org/2003/role/presentationRef
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Reference 7: http://www.xbrl.org/2003/role/presentationRef
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Reference 8: http://www.xbrl.org/2003/role/presentationRef
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Reference 9: http://www.xbrl.org/2003/role/presentationRef
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-Name Accounting Standards Codification
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Reference 10: http://www.xbrl.org/2003/role/presentationRef
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-Name Accounting Standards Codification
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Reference 13: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
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Reference 14: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
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Reference 15: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
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-URI http://asc.fasb.org/extlink&oid=35744584&loc=d3e6996-128479

+ Details

Restricted Cash and Short-Term Investments

12 Months Ended

Dec. 31, 2016

Cash and Cash Equivalents [Abstract]

Restricted Cash and Short-Term Investments

NOTE 4. RESTRICTED CASH AND SHORT-TERM INVESTMENTS

The restricted cash and short-term investments at December 31, 2016 and 2015 consist of a money market account and certificates of deposit, which are classified as held-to-maturity. At December 31, 2016 and 2015, the restricted short-term investments were recorded at amortized cost which approximates fair value.

At December 31, 2016 and 2015, the money market account and the certificates of deposit of $200 and $150, respectively, were classified as a current asset. The certificates of deposit that were required as collateral under the Company’s corporate credit card agreement and as additional security for the Company’s office space lease were redeemed during the year ended December 31, 2016. The money market account is required for additional security for the Company’s New Jersey based facility.

Inventories

12 Months Ended

Dec. 31, 2016

Inventory Disclosure [Abstract]

Inventories

NOTE 5. INVENTORIES

Inventories are comprised of over-the-counter and prescription retail pharmacy products, commercial pharmaceutical products, related laboratory supplies and active pharmaceutical ingredients. The composition of inventories, net of reserve, as of December 31, 2016 and 2015 was as follows:

	December 31, 2016		December 31, 2015
Raw materials	$	669	$	775
Finished goods		1,172		637
Total inventories	$	1,841	$	1,412

Prepaid Expenses and Other Current Assets

12 Months Ended

Dec. 31, 2016

Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Abstract]

Prepaid Expenses and Other Current Assets

NOTE 6. PREPAID EXPENSES AND OTHER CURRENT ASSETS

Prepaid expenses and other current assets at December 31, 2016 and 2015 consisted of the following:

	December 31, 2016		December 31, 2015
Prepaid insurance	$	315	$	297
Other prepaid expenses		517		370
Deposits and other current assets		106		119
Total prepaid expenses and other current assets	$	938	$	786

Property, Plant and Equipment

12 Months Ended

Dec. 31, 2016

Property, Plant and Equipment [Abstract]

Property, Plant and Equipment

NOTE 7. PROPERTY, PLANT AND EQUIPMENT

Property, plant and equipment at December 31, 2016 and 2015 consisted of the following:

	December 31, 2016			December 31, 2015
Property, plant and equipment, net:
Computer software and hardware	$	831		$	323
Furniture and equipment		424			350
Lab and pharmacy equipment		2,559			538
Leasehold improvements		4,836			1,746
		8,650			2,957
Accumulated depreciation and amortization		(1,355	)		(300	)
	$	7,295		$	2,657

The Company recorded depreciation and amortization expense of $1,055 and $255 during the years ended December 31, 2016 and 2015, respectively.

Intangible Assets and Goodwill

12 Months Ended

Dec. 31, 2016

Goodwill and Intangible Assets Disclosure [Abstract]

Intangible Assets and Goodwill

NOTE 8. INTANGIBLE ASSETS AND GOODWILL

The Company’s intangible assets at December 31, 2016 consisted of the following:

	Amortization
	periods			Accumulated						Net
	(in years)	Cost		amortization			Impairment			Carrying value
Patents	17-19 years	$	214	$	(6	)	$	-		$	208
Trademarks	Indefinite		224		-			-			224
Customer relationships	3-15 years		2,998		(554	)		(15	)		2,429
Trade name	5 years		16		(7	)		(1	)		8
Non-competition clause	3-4 years		294		(184	)		(20	)		90
State pharmacy licenses	25 years		45		(4	)		(28	)		13
		$	3,791	$	(755	)	$	(64	)	$	2,972

The Company’s intangible assets at December 31, 2015 consisted of the following:

	Amortization
	periods			Accumulated			Net
	(in years)	Cost		amortization			Carrying value
Patents	17-19 years	$	64	$	(1	)	$	63
Trademarks	Indefinite		121		-			121
Customer relationships	3-15 years		2,998		(297	)		2,701
Trade name	5 years		16		(4	)		12
Non-competition clause	3-4 years		294		(99	)		195
State pharmacy licenses	25 years		45		(2	)		43
		$	3,538	$	(403	)	$	3,135

Amortization expense for intangible assets for the years ended December 31, 2016 and 2015 was as follows:

	For the		For the
	Year Ended		Year Ended
	December 31, 2016		December 31, 2015
Patents	$	5	$	1
Customer relationships		255		260
Trade name		3		3
Non-competition clause		86		90
State pharmacy licenses		2		1
	$	351	$	355

Estimated future amortization expense for the Company’s intangible assets at December 31, 2016 is as follows:

Years ending December 31,
2017	$	359
2018		218
2019		215
2020		212
2021		212
Thereafter		1,755
	$	2,972

The changes in the carrying value of the Company’s goodwill during the years ended December 31, 2016 and 2015 were as follows:

Balance at January 1, 2015	$	332
Acquisition of Park (see Note 3)		1,895
Acquisition of CAP (see Note 3)		239
Balance at December 31, 2015		2,466
Impairment of CAP (see Note 2)		(239	)
Balance at December 31, 2016	$	2,227

- Definition

The entire disclosure for the aggregate amount of goodwill and a description of intangible assets, which may include (a) for amortizable intangible assets (also referred to as finite-lived intangible assets), the carrying amount, the amount of any significant residual value, and the weighted-average amortization period, (b) for intangible assets not subject to amortization (also referred to as indefinite-lived intangible assets), the carrying amount, and (c) the amount of research and development assets acquired and written off in the period, including the line item in the income statement in which the amounts written off are aggregated, if not readily apparent from the income statement. Also discloses (a) for amortizable intangibles assets in total and by major class, the gross carrying amount and accumulated amortization, the total amortization expense for the period, and the estimated aggregate amortization expense for each of the five succeeding fiscal years, (b) for intangible assets not subject to amortization the carrying amount in total and by major class, and (c) for goodwill, in total and for each reportable segment, the changes in the carrying amount of goodwill during the period (including the aggregate amount of goodwill acquired, the aggregate amount of impairment losses recognized, and the amount of goodwill included in the gain (loss) on disposal of a reporting unit). If any part of goodwill has not been allocated to a reportable segment, discloses the unallocated amount and the reasons for not allocating. For each impairment loss recognized related to an intangible asset (excluding goodwill), discloses: (a) a description of the impaired intangible asset and the facts and circumstances leading to the impairment, (b) the amount of the impairment loss and the method for determining fair value, (c) the caption in the income statement or the statement of activities in which the impairment loss is aggregated, and (d) the segment in which the impaired intangible asset is reported. For each goodwill impairment loss recognized, discloses: (a) a description of the facts and circumstances leading to the impairment, (b) the amount of the impairment loss and the method of determining the fair value of the associated reporting unit, and (c) if a recognized impairment loss is an estimate not finalized and the reasons why the estimate is not final. May also disclose the nature and amount of any significant adjustments made to a previous estimate of an impairment loss.

+ References + Details

Accounts Payable and Accrued Expenses

12 Months Ended

Dec. 31, 2016

Payables and Accruals [Abstract]

Accounts Payable and Accrued Expenses

NOTE 9. ACCOUNTS PAYABLE AND ACCRUED EXPENSES

Accounts payable and accrued expenses at December 31, 2016 and 2015 consisted of the following:

	December 31, 2016			December 31, 2015
Accounts payable	$	2,999		$	3,185
Deferred rent		412			63
Accrued interest (see Note 10)		116			90
Accrued exit fee for note payable (see Note 10)		667			500
Building lease liability(1)		11			46
Other accrued expenses (2)		-			23
Total accounts payable and accrued expenses		4,205			3,907
Less: Current portion		(3,538	)		(3,407	)
Non-current total accrued expenses	$	667		$	500

	(1)	In September 2014, the Company relocated its primary operations to a 7,565 square foot office facility in San Diego, California. In February 2015, the Company entered into a sublease agreement to sublet 3,874 square feet of its previously occupied offices through the remaining term of the lease at a monthly rent amount of $8. The Company recognized a loss of approximately $117 during the year ended December 31, 2014 related to the estimated remaining lease liability, net of expected sublease income, of the previously occupied offices. In September 2016, the Company decided to cease operations at its Texas location and started steps to wind down operations. The Company recognized a loss of $16 during the year ended December 31, 2016 related to the estimated remaining lease liability. The obligations were discounted based on current prevailing market rates.

	(2)	The amount consists of a $23 stock-based compensation accrual at December 31, 2015, for stock options to be granted for services performed. The stock-based compensation expense related to the accruals was $23 during the year ended December 31, 2015. The $23 was recorded to additional paid-in-capital upon issuance of the stock options in 2016.

Debt

12 Months Ended

Dec. 31, 2016

Debt Disclosure [Abstract]

Debt

NOTE 10. DEBT

Senior Note – 2015

On May 11, 2015, the Company entered into a loan and security agreement (the “Loan Agreement”) with IMMY Funding LLC, an affiliate of Life Sciences Alternative Funding LLC (the “Lender”), as lender and collateral agent. Pursuant to the terms of the Loan Agreement, as amended in January 2016 and December 2016 (see further description of December 2016 amendment below), the Lender made available to the Company a term loan in the aggregate principal amount of up to $10,000, all of which was drawn on May 11, 2015. The term loan bore interest at a fixed per-annum rate of 12.5% and allowed for 2% of the interest to be paid-in-kind until December 2016. The Company was permitted to pay interest only until June 1, 2017. The Company is required to pay interest, plus repayments of the principal amount of the term loan, in 20 equal monthly installments. All amounts owed under the Loan Agreement, including a final fee of 5% of the aggregate principal amount of the term loan and prepayment fees of up to 1% of the principal balance are due on January 1, 2019 . The Company incurred expenses of approximately $1,066 in connection with the Loan Agreement. The final fee and expenses are being amortized as interest expense over the term of the debt using the interest method and the related liability of $667 and $500 for the final fee, as of December 31, 2016 and 2015, respectively, is included in accrued expenses (see Note 9) in the accompanying consolidated balance sheets.

Pursuant to the terms of the Loan Agreement, the Company is bound by certain affirmative covenants setting forth actions that the Company must take during the term of the Loan Agreement, including, among others, certain information delivery requirements, obligations to maintain certain insurance and certain notice requirements. Additionally, the Company is bound by certain negative covenants setting forth actions that the Company may not take during the term of the Loan Agreement without the Lender’s consent, including, among others, disposing of certain of the Company’s or its subsidiaries’ business or property, incurring certain additional indebtedness, entering into certain merger, acquisition or change of control transactions, paying certain dividends or distributions on or repurchasing any of the Company’s capital stock, or incurring any lien or other encumbrance on the Company’s or its subsidiaries’ assets, subject to certain permitted exceptions. Upon the occurrence of an event of default under the Loan Agreement (subject to cure periods for certain events of default), all amounts owed by the Company thereunder may be declared immediately due and payable by the Lender. Events of default include, among others, the following: the occurrence of certain bankruptcy events; the failure to make payments under the Loan Agreement when due; the occurrence of a material adverse change in the business, operations or condition of the Company or any of its subsidiaries; the breach by the Company or its subsidiaries of certain of their material agreements with third parties; the initiation of certain regulatory enforcement actions against the Company or its subsidiaries; the rendering of certain types of fines or judgments against the Company or its subsidiaries; any breach by the Company or its subsidiaries of any covenant (subject to cure periods for certain covenants) made in the Loan Agreement; and the failure of any representation or warranty made by the Company or its subsidiaries in connection with the Loan Agreement to be correct in any material respect when made.

The Company’s obligations under the Loan Agreement are guaranteed on a secured basis by its wholly owned subsidiaries. Each of the Company and its subsidiaries has granted the Lender a security interest in substantially all of its personal property, rights and assets, including intellectual property rights and equity ownership, to secure the payment of all amounts owed under the Loan Agreement.

In connection with the Loan Agreement, the Company issued to the Lender a warrant to purchase up to 125,000 shares of the Company’s common stock, which is exercisable immediately, has an exercise price of $7.85 per share upon issuance and has a term of 10 years. The relative fair value of the warrants was approximately $840 and was estimated using the Black-Scholes-Merton option pricing model with the following assumptions: fair value of the Company’s common stock at issuance of $7.97 per share; ten-year contractual term; 109% volatility; 0% dividend rate; and a risk-free interest rate of 1.25%. The relative fair value of the warrants was recorded as a debt discount, decreasing notes payable and increasing additional paid-in capital on the accompanying consolidated balance sheet. The debt discount is being amortized to interest expense over the term of the debt using the interest method. As described further, this warrant was amended in January 2016 and December 2016. For the years ended December 31, 2016 and 2015, debt discount amortization related to the Loan Agreement was $470 and $281, respectively.

Convertible Senior Note – 2016

On January 22, 2016, the Company entered into a note purchase agreement (the “NPA”) with, and issued an 8.00% Convertible Senior Secured Note (“Convertible Note”) in the principal amount of $3,000 to, the Lender. Pursuant to the terms of the NPA, on the date thereof, the Company issued the Convertible Note to the Lender and, as consideration therefor, the Lender paid the Company in cash the full principal amount of the Convertible Note. The Company incurred expenses of approximately $228 in connection with the Convertible Note and these expenses were recorded as a debt discount. The debt discount is being amortized as interest expense over the term of the debt using the effective interest method.

Pursuant to the terms of the Convertible Note, the Company is obligated to pay interest on the principal amount of the Convertible Note monthly in cash at a fixed per-annum rate of 8.00%, and the Company is obligated to repay the full principal amount of the Convertible Note in cash on May 11, 2021. The Company is permitted to redeem the Convertible Note prior to its maturity at any time on or after March 1, 2018 for cash purchase prices equal to 109% - 105% of the outstanding principal amount of the Convertible Note, depending on the date of redemption. The Convertible Note was initially convertible by the holder at any time into shares of the Company’s common stock at an effective conversion price of approximately $5.90 and subject to anti-dilution adjustment upon the Company’s first equity financing while the Convertible Note is outstanding in which it receives gross proceeds of at least $3,000, if such equity financing is completed at a per share price that is less than the conversion rate of the Convertible Note, and also subject to adjustment upon stock combinations or splits, certain recapitalizations, stock or cash dividends or other distributions of property or equity rights. Additionally, in the event of certain change of control events affecting the Company, the Company may be required, at the option of the Lender, to repurchase the Convertible Note in cash for the greater of 105% of the outstanding principal amount of the Convertible Note or the value of the shares of common stock issuable upon conversion of the Convertible Note. The fair value of the conversion feature was $2,322 and was recorded as a debt discount, decreasing notes payable and increasing additional paid-in capital on the accompanying consolidated balance sheet (see also Note 12). The debt discount is being amortized to interest expense over the term of the debt using the effective interest method. For the year ended December 31, 2016, debt discount amortization related to the Convertible Note was $534.

In connection and concurrently with the execution of the NPA and the issuance of the Convertible Note, the Company and the Lender also entered into an amendment (the “Loan Agreement Amendment”) to the Loan Agreement (see above). The Loan Agreement Amendment modifies the terms of the Loan Agreement in order to eliminate the potential borrowing of a second term loan thereunder and to permit the Company to issue the Convertible Note. Additionally, the Company and the Lender entered into an amendment (the “Warrant Amendment”) to the warrants that were issued to the Lender in connection with the Loan Agreement. The Warrant Amendment modifies the terms of the warrants in order to reduce the exercise price thereof to $5.90 per share, which is consistent with the initial conversion rate of the Convertible Note, and to add an anti-dilution adjustment provision that is consistent with the same such provision in the Convertible Note.

On March 16, 2016, upon the closing of the Offering (see Note 12) and pursuant to the anti-dilution adjustment provisions of the Convertible Note and the Warrant Amendment, the effective conversion price of the Convertible Note was adjusted to approximately $3.60, and the exercise price of the warrants was adjusted to $3.60 per share (see also Note 12 for further accounting discussion of the warrant exercise price and conversion provisions and related derivative liabilities). The warrant was amended again in December 2016, to modify the exercise price to $1.79 per share, in connection with the Exchange Agreement (described below).

On December 27, 2016, the Company entered into a third amendment (the “Amendment”) to the Loan Agreement with the Lender. Concurrently with entering into and related to the Amendment, the Company and the Lender also entered into an Exchange and Discharge Agreement (the “Exchange Agreement”). The Amendment and Exchange Agreement, among other things, primarily allowed for the Company and the Lender to exchange the Convertible Note for a $3,000 term loan (the “Term B Loan”). The Term B Loan was issued in exchange for, and not funded separately, cancellation and discharge of all indebtedness related to the Convertible Note. Terms, conditions and security interests of the Term B Loan are substantially equal to those of the Loan Agreement. The Amendment also amended certain terms and definitions associated with prepayment, payment schedule, amortization periods and defined the outstanding principal amounts due to the Lender under the Loan Agreement and Term B Loan, including any interest that has been paid in kind of the principal balance, in aggregate, as $13,332. In connection with the Exchange Agreement, during the year ended December 31, 2016, the Company recorded early extinguishment expense of $1,966 for remaining unamortized debt discounts related to the Convertible Note at the time of the Exchange Agreement.

Notes payable at December 31, 2016 were as follows:

	December 31, 2016
December 2016 Amended Note	$	13,332
Less: Discount on notes		(1,422	)
Less: Current portion		(4,999	)
Long-term portion	$	6,911

Future minimum payments under notes payable outstanding at December 31, 2016 are as follows:

Year Ending December 31, 2016	Amount
2017	$	6,485
2018		8,905
Total minimum payments		15,390
Less: amount representing interest		(2,058	)
Notes payable, gross		13,332
Less: unamortized discount		(1,422	)
Note payable, net of unamortized debt discount	$	11,910

Capital Lease Obligation

12 Months Ended

Dec. 31, 2016

Leases [Abstract]

Capital Lease Obligation

NOTE 11. CAPITAL LEASE OBLIGATION

On August 9, 2016, the Company entered into a commercial lease agreement (the “Lease Agreement”) with Essex Capital Corporation (“Essex”). Pursuant to the terms of the Lease Agreement, the Company sold certain equipment (the “Equipment”) to Essex for a total purchase price of approximately $2,000, which was then leased back to the Company under a thirty-six month term net basis lease with monthly payments of approximately $64. The fair value of equipment sold and then leased under the Lease Agreement totaled approximately $2,000. The lease term may be extended for an additional twelve month period in the event the Company achieves certain financial milestones. The Company has the right to purchase the Equipment from Essex upon the expiration of the Lease Agreement for a purchase price equal to the Equipment’s then fair market value, with such fair market value not to exceed fifteen percent of the original Equipment value on August 9, 2016. If the Equipment is not purchased at the end of the term, the Company may automatically extend the lease on a month-to-month basis or return the Equipment and terminate the Lease Agreement. The Company expects to purchase the Equipment at the end of the term of the lease and has accrued the final payment amount of $300. The Company also incurred expenses of approximately $67 in connection with the Lease Agreement. The issuance costs were recorded as a discount. The discount is being amortized as interest expense over the term of the lease using the effective interest method. The Company used an interest rate of 16.8% for calculation of the present value of the future minimum payments under the Lease Agreement. For the year ended December 31, 2016, debt discount amortization related to the Lease Agreement was $90 and is included in interest expense in the accompanying consolidated statement of operations.

At December 31, 2016, future payments under the Company’s capital lease were as follows:

	Amount
2017	$	773
2018		773
2019		751
Total minimum lease payments		2,297
Less: amount representing interest payments		(244	)
Present value of future minimum lease payments		2,053
Less: unamortized discount		(277	)
		1,776
Less: current portion, net of unamortized discount		(458	)
Capital lease obligation, net of current portion and unamortized discount	$	1,318

The value of the equipment under capital leases as of December 31, 2016 and 2015 was $2,070 and $60, respectively, with related accumulated depreciation of $293 and $9, respectively.

Stockholders' Equity (Deficit) and Stock-Based Compensation

12 Months Ended

Dec. 31, 2016

Equity [Abstract]

Stockholders' Equity (Deficit) and Stock-Based Compensation

NOTE 12. STOCKHOLDERS’ EQUITY (DEFICIT) AND STOCK-BASED COMPENSATION

Common Stock

At December 31, 2016 and 2015, the Company had 90,000,000 shares of common stock, $0.001 par value, authorized.

Issuances During the Year Ended December 31, 2015

During the year ended December 31, 2015, the Company issued a total of 130,457 shares of common stock as a result of option exercises. The Company received no cash proceeds for the issuance of the shares of common stock upon the exercise pursuant to cashless exercise provisions of stock options to purchase 255,600 shares of common stock with exercise prices ranging from $3.20 to $4.51 per share.

During the year ended December 31, 2015, the Company issued 1,611 shares of common stock to employees related to the vesting of RSUs, net of 1,241 shares of common stock withheld for payroll tax withholdings totaling $10.

In January 2015, the Company issued 8,521 shares of its common stock in connection with RSUs that had been awarded to a non-employee director and had vested, but were not issued and settled until the resignation of the director on January 1, 2015.

During the year ended December 31, 2015, the Company issued a total of 220,912 shares of common stock as a result of warrant exercises. Of these, the Company received cash proceeds of $1,248 for the issuance of 209,980 shares of common stock upon the exercise on a cash basis of warrants to purchase the same number of shares of common stock with an exercise price of $5.925, and the Company received no cash proceeds for the issuance of 10,932 shares of common stock upon the exercise pursuant to cashless exercise provisions of warrants to purchase 30,457 shares of common stock with an exercise price of $5.25 per share.

In November 2015, the Company entered into a Controlled Equity Offering^SM sales agreement (the “Sales Agreement”) with Cantor Fitzgerald & Co., as agent (“Cantor Fitzgerald”), pursuant to which the Company may offer and sell, from time to time through Cantor Fitzgerald, shares of our common stock having an aggregate offering price as set forth in the Sales Agreement and a related prospectus supplement filed with the Securities and Exchange Commission. The Company agreed to pay Cantor Fitzgerald a cash commission of 3.0% of the aggregate gross proceeds from each sale of shares under the Sales Agreement and to reimburse Cantor Fitzgerald for certain fees and expenses in an amount not to exceed $50. During the fourth quarter of 2015, 72,421 shares of common stock were sold under the Sales Agreement for gross proceeds of approximately $529 and net proceeds, after deducting $16 in commission fees and $109 in offering expenses payable by the Company, of approximately $404.

In January 2015, the Company issued 63,525 shares of restricted common stock, valued at $425, in connection with the Park Acquisition (see Note 3).

During the year ended December 31, 2015, 28,606 shares of the Company’s common stock underlying RSUs issued to directors vested, but the issuance and delivery of these shares are deferred until the director resigns.

Issuances During the Year Ended December 31, 2016

In March 2016, the Company entered into an underwriting agreement (the “Underwriting Agreement”) with National Securities Corporation and several other underwriters, under which the Company sold in a firm-commitment public offering (the “Offering”), 3,335,000 shares of the Company’s common stock at $3.60 per share. The Offering closed on March 16, 2016. The Company received net proceeds of $11,088, after deducting the underwriting discount and the offering expenses payable by the Company.

The Company sold 57,042 shares of common stock and received net proceeds of $212, after deducting $20 for sales commission and offering expenses, under the Sales Agreement during the year ended December 31, 2016, leaving an aggregate of $1,871 available for future sales of shares thereunder as of December 31, 2016.

In May 2016, we issued 75,000 shares of the Company’s common stock, with a fair value of $302, as a contingent payment related to the acquisition of PC (see Note 16).

In October 2016, the Company issued 16,076 shares of its common stock in connection with RSUs that had been awarded to a non-employee director and had vested, but were not issued and settled until the resignation of the director in September 2016.

In December 2016, the Company issued 116,291 shares of its common stock to its CEO, Mark L. Baum, in connection with 200,000 RSUs that had vested in May 2016. The issuance of common stock was net of 83,709 shares of common stock withheld for payroll tax withholdings totaling $144.

In December 2016, the Company entered into a securities purchase agreement with certain purchasers, which provided for the sale of 5,257,828 Units, with each Unit consisting of one share of common stock of the Company, and one warrant to purchase one share of common stock (the “Investor Warrants”), at a price of $1.915 per Unit for aggregate net proceeds of approximately $9,217 after deducting $852 in placement agent fees and offering expenses (the “PIPE Offering”). The Investor Warrants have an exercise price of $1.79 per share, are non-exercisable for the first six months and will expire three years from the date of issuance. The Company paid National Securities Corporation (the “Placement Agent”), in consideration for its services as placement agent for the PIPE Offering, a cash amount equal to 7.5% of the gross proceeds from the sale of the Units. The Company also issued to the Placement Agent a warrant (the “Agent Warrant”) to purchase up to 210,313 shares of the Company’s common stock. The Agent Warrant was issued on the same terms and conditions of the Investor Warrants.

During the year ended December 31, 2016, the Company issued a total of 15,000 shares of common stock as a result of option exercises. The Company received $55 in cash proceeds for the issuance of the shares of common stock upon the exercise pursuant to exercise provisions of stock options to purchase 15,000 shares of common stock with exercise price of $3.68 per share.

During the year ended December 31, 2016, 24,421 shares of the Company’s common stock underlying RSUs issued to directors vested, but the issuance and delivery of these shares are deferred until the director resigns.

Preferred Stock

At December 31, 2016 and 2015, the Company had 5,000,000 shares of preferred stock, $0.001 par value, authorized and no shares of preferred stock issued and outstanding.

Stock Option Plan

On September 17, 2007, the Company’s Board of Directors and stockholders adopted the Company’s 2007 Incentive Stock and Awards Plan, which was subsequently amended on November 5, 2008, February 26, 2012, July 18, 2012, May 2, 2013 and September 27, 2013 (as amended, the “Plan”). As of December 31, 2016, the Plan provides for the issuance of a maximum of 5,000,000 shares of the Company’s common stock. The purpose of the Plan is to provide an incentive to attract and retain directors, officers, consultants, advisors and employees whose services are considered valuable, to encourage a sense of proprietorship and to stimulate an active interest of such persons in the Company’s development and financial success. Under the Plan, the Company is authorized to issue incentive stock options intended to qualify under Section 422 of the Internal Revenue Code, non-qualified stock options, RSUs and restricted stock. The Plan is administered by the Compensation Committee of the Company’s Board of Directors. The Company had 815,159 shares available for future issuances under the Plan at December 31, 2016.

Stock Options

A summary of the stock option activity under the Plan for the year ended December 31, 2016 is as follows:

	Number of shares			Weighted Avg. Exercise Price		Weighted Avg. Remaining Contractual Life		Aggregate Intrinsic Value
Options outstanding - January 1, 2016		1,544,026		$	5.74
Options granted		549,350		$	3.99
Options exercised		(15,000	)	$	3.68
Options cancelled/forfeit		(65,063	)	$	7.80
Options outstanding - December 31, 2016		2,013,313			6.20		6.28	$	13
Options exercisable		808,067			6.18		5.75	$	13
Options vested and expected to vest		1,892,790			6.20		6.10	$	13

The aggregate intrinsic value in the table above represents the total pre-tax amount of the proceeds, net of exercise price, which would have been received by option holders if all option holders had exercised and immediately sold all options with an exercise price lower than the market price on December 31, 2016, based on the closing price of the Company’s common stock of $2.50 on that date. The aggregate intrinsic value of stock options exercised during the year ended December 31, 2016 was approximately $29.

During 2016 and 2015, the Company granted stock options to certain employees, directors and consultants. The stock options were granted with an exercise price equal to the current market price of the Company’s common stock, as reported by the securities exchange on which the common stock was then listed, at the grant date and have contractual terms ranging from five to 10 years. Vesting terms for options granted in 2016 and 2015 to employees, directors and consultants typically included one of the following vesting schedules: 25% of the shares subject to the option vest and become exercisable on the first anniversary of the grant date and the remaining 75% of the shares subject to the option vest and become exercisable quarterly in equal installments thereafter over three years; quarterly vesting over three years; or 100% vesting associated with the provision or completion of services provided under contracts with consultants. Certain option awards provide for accelerated vesting if there is a change in control (as defined in the Plan) and in the event of certain modifications to the option award agreement.

The fair value of each option award is estimated on the date of grant using the Black-Scholes-Merton option pricing model. The expected volatility is based on the historical volatilities of the common stock of the Company and comparable publicly traded companies based on the Company’s belief that it currently has limited relevant historical data regarding the volatility of its stock price on which to base a meaningful estimate of expected volatility. The expected term of options granted was determined in accordance with the “simplified approach,” as the Company has limited, relevant, historical data on employee exercises and post-vesting employment termination behavior. The expected risk-free interest rate is based on the U.S. Treasury yield for a period consistent with the expected term of the option in effect at the time of the grant. The financial statement effect of forfeitures is estimated at the time of grant and revised, if necessary, if the actual effect differs from those estimates. For option grants to employees and directors, the Company assigns a forfeiture factor of 10%. These factors could change in the future, which would affect the determination of stock-based compensation expense in future periods. Utilizing these assumptions, the fair value is determined at the date of grant.

On July 31, 2015, the Company granted to its Chief Executive Officer, Mark Baum, an option (the “Baum Performance Option”) to purchase 600,000 shares of the Company’s common stock at an exercise price of $7.87 per share under the Plan subject to the satisfaction of certain market-based vesting criteria. The market-based vesting criteria are separated into five tranches and require that the Company achieve and maintain certain average stock price targets ranging from $9 per share to $15 per share during the five year period following the grant date. These market-based vesting conditions are as follows:

Tranche	Number of Shares	Target Share Price
Tranche 1	200,000 shares	$9.00 or greater
Tranche 2	100,000 shares	$10.00 or greater
Tranche 3	100,000 shares	$12.00 or greater
Tranche 4	100,000 shares	$14.00 or greater
Tranche 5	100,000 shares	$15.00 or greater

The Baum Performance Option terminates on the fifth anniversary of the grant date. The fair value of the Baum Performance Option was $2,784 using a Monte Carlo Simulation with a five-year life, 80% volatility and a risk free interest rate of 1.54 %.

The table below illustrates the fair value per share determined using the Black-Scholes-Merton option pricing model with the following assumptions used for valuing options granted to employees and directors:

	2016			2015
Weighted-average fair value of options granted	$	3.91		$	6.22
Expected terms (in years)		5.81 - 6.11			5.81 - 6.11
Expected volatility		101 - 112	%		101 - 121	%
Risk-free interest rate		1.07 - 1.70	%		1.39 - 1.68	%
Dividend yield		-			-

The table below illustrates the fair value per share determined using the Black-Scholes-Merton option pricing model with the following assumptions used for valuing options granted to consultants:

	2016			2015
Weighted-average fair value of options granted	$	6.18		$	6.49
Expected terms (in years)		10			10
Expected volatility		109	%		108 - 109	%
Risk-free interest rate		1.06	%		1.06 - 1.63	%
Dividend yield		-			-

The following table summarizes information about stock opt0ions outstanding and exercisable at December 31, 2016:

	Options Outstanding						Options Exercisable
			Weighted
			Average		Weighted				Weighted
			Remaining		Average				Average
	Number		Contractual		Exercise		Number		Exercise
Range of Exercise Prices	Outstanding		Life in Years		Price		Exercisable		Price
$2.40 - $2.60		147,000		5.80	$	2.43		125,000	$	2.40
$3.74 - $4.50		695,623		7.69	$	4.05		225,256	$	4.25
$5.49 - $7.99		952,103		5.01	$	7.54		249,857	$	6.83
$8.06 - $8.99		213,557		6.10	$	8.92		202,924	$	8.95
$42.80		5,030		3.87	$	42.80		5,030	$	42.80
		2,013,313		6.28	$	6.20		808,067	$	6.18

As of December 31, 2016, there was approximately $5,116 of total unrecognized compensation expense related to unvested stock options granted under the Plan. That expense is expected to be recognized over the weighted-average remaining vesting period of 3.1 years. The stock-based compensation for all stock options was $2,159 and $1,747 during the years ended December 31, 2016 and 2015, respectively.

Restricted Stock Units

RSU awards are granted subject to certain vesting requirements and other restrictions, including performance and market based vesting criteria. The grant-date fair value of the RSUs, which has been determined based upon the market value of the Company’s common stock on the grant date, is expensed over the vesting period of the RSUs. Unvested portions of RSUs issued to consultants are remeasured on an interim basis until vesting criteria is met.

Grants During the Year Ended December 31, 2015

During February 2015, the Company granted 30,000 RSUs to its Chief Financial Officer, Andrew R. Boll and 30,000 RSUs to its Chief Commercial Officer, John P. Saharek, valued at $442 in the aggregate. The RSUs were granted pursuant to the Plan and will vest on the third anniversary of the RSU grant date, subject to the applicable employee’s continued employment with the Company on such date and accelerated vesting of all unvested shares thereunder upon the occurrence of a change in control (as defined in the Plan).

During February 2015, the Company granted 157,500 RSUs to Mr. Boll, which are subject to the satisfaction of certain market-based and continued service conditions (the “Boll Performance Equity Award”). The market-based vesting criteria are separated into five tranches and require that the Company achieve and maintain certain stock price targets ranging from $10 per share to $30 per share during the three-year period following the grant date. With certain limited exceptions, Mr. Boll must be employed with the Company on the third anniversary of the grant date in order for the Boll Performance Equity Award to vest.

The market-based vesting conditions applicable to the Boll Performance Equity Award are as follows:

Tranche	Number of Shares	Target Share Price
Tranche 1	30,000 shares	$10.00 or greater
Tranche 2	30,000 shares	$15.00 or greater
Tranche 3	30,000 shares	$20.00 or greater
Tranche 4	30,000 shares	$25.00 or greater
Tranche 5	37,500 shares	$30.00 or greater

The initial fair value of the Boll Performance Equity Award was $228 using a Monte Carlo Simulation with a three-year life, 60% volatility and a risk free interest rate of 0.77%.

During the year ended December 31, 2015, the Company granted an aggregate of 34,166 RSUs to its non-employee directors valued at $270. These RSUs vest in equal quarterly installments over a one year period subject to the director’s continued service at the vesting date, but the issuance and delivery of these shares are deferred until the director resigns.

Grants During the Year Ended December 31, 2016

In April 2016, the Company granted performance-based RSU awards to its CEO, Mark L. Baum, of up to 1,050,000 performance stock units and to its CFO, Andrew R. Boll, of up to 157,500 performance stock units. The performance stock units will vest on the fifth anniversary of the grant date, subject to Mr. Baum’s and Mr. Boll’s continued employment with the Company, respectively, and may vest earlier if the Company achieves and maintains certain stock price targets during the five year period following the grant date or upon a change in control if the performance-based equity award is not assumed, continued or substituted for by the acquiring entity. The market-based accelerated vesting criteria are broken into five equal tranches and require that the Company achieve and maintain certain stock price targets ranging from $9 per share to $15 per share during the five-year period following the grant date. These market-based accelerated vesting conditions and share amounts (in aggregate) are set forth below:

Tranche	Number of shares	Target share price
Tranche 1	230,000 shares	$9.00 or greater
Tranche 2	230,000 shares	$10.00 or greater
Tranche 3	230,000 shares	$12.00 or greater
Tranche 4	230,000 shares	$14.00 or greater
Tranche 5	287,500 shares	$15.00 or greater

For each respective tranche to vest the following conditions must be met: (i) the Company’s common stock must have an official closing price at or above the target share price for the respective tranche (each such date, a “Trigger Date”); (ii) during the period that includes the Trigger Date and the immediately following 19 trading days (the “Measurement Period”), the arithmetic mean of the 20 closing prices of the Company’s common stock during the Measurement Period must be at or above the target share price for such tranche; and (iii) with certain limited exceptions, the executive must be in service with the Company through the date of vesting.

Concurrent with the issuance of the performance-based restricted stock unit awards, Mr. Baum agreed to forfeit 1,050,000 RSUs subject to performance-based vesting granted to him in May 2013 and Mr. Boll agreed to forfeit the Boll Performance Equity Award granted to him in February 2015. As a result, the issuance of the performance-based RSUs awarded in April 2016 have been treated as modifications of the RSUs granted to Mr. Baum in May 2013 and Mr. Boll in February 2015 for accounting purposes. The Company used a lattice binomial model to estimate a derived service period of 33 months related to the performance-based vesting grants and used the following assumptions:

	2016
Market price	$	3.98
Contractual terms (in years)		5.00
Expected volatility		102	%
Risk-free interest rate		1.04	%
Dividend yield		-

During the year ended December 31, 2016, the Company granted an aggregate of 63,450 RSUs to its non-employee directors valued at $250. These RSUs vest in equal quarterly installments over a one year period subject to the director’s continued service at the vesting date, but the issuance and delivery of these shares are deferred until the director resigns.

A summary of the Company’s RSU activity and related information for the year ended December 31, 2016 is as follows:

	Number of RSUs			Weighted Average Grant Date Fair Value
RSUs unvested - January 1, 2016		1,487,961		$	3.18
RSUs granted		1,270,950		$	2.25
RSUs vested		(249,018	)	$	8.32
RSUs cancelled/forfeit		(1,217,017	)	$	1.95
RSUs unvested at December 31, 2016		1,292,876		$	2.43

As of December 31, 2016, the total unrecognized compensation expense related to unvested RSUs was approximately $3,873 which is expected to be recognized over a weighted-average period of 1.8 years, based on estimated vesting schedules. The stock-based compensation for RSUs was $1,539 and $1,671 during the years ended December 31, 2016 and 2015, respectively.

The Company recorded stock-based compensation (including issuance of common stock for services and accrual for stock-based compensation) related to equity instruments granted to employees, directors and consultants as follows:

	For the		For the
	Year Ended		Year Ended
	December 31, 2016		December 30, 2015
Employees - selling and marketing	$	498	$	370
Employees - general and administrative		2,954		2,720
Directors - general and administrative		221		268
Consultants - selling and marketing		-		83
Other - general and administrative		115		-
Total	$	3,788	$	3,441

Warrants

From time to time, the Company issues warrants to purchase shares of the Company’s common stock to investors, lenders (see Note 10), underwriters and other non-employees for services rendered or to be rendered in the future.

A summary of warrant activity during the year ended December 31, 2016 is as follows:

	Number of Shares Subject to Warrants Outstanding		Weighted Avg. Exercise Price

Warrants outstanding - January 1, 2016		240,688	$	7.41
Granted		5,508,141	$	1.80
Exercised		-
Expired		-
Warrants outstanding and exercisable - December 31, 2016		5,748,829	$	1.91
Weighted average remaining contractual life of the outstanding warrants in years - December 31, 2016		3.08

The table below illustrates the fair value per share determined by the Black-Scholes-Merton option pricing model with the following assumptions used for valuing warrants granted related to settlement agreements:

	2016
Weighted-average fair value of warrants granted		2.88
Expected terms (in years)		5
Expected volatility		106	%
Risk-free interest rate		0.79	%
Dividend yield		-

All warrants outstanding as of December 31, 2016 are included in the following table:

	Warrants Outstanding						Warrants Exercisable
			Warrants		Exercise		Warrants		Expiration
Warrant Series	Issue Date		Outstanding		Price		Exercisable		Date
Lender warrants (see Note 10)		5/11/2015		125,000	$	1.79		125,000		5/11/2025
Underwriter warrants		2/7/2013		55,688	$	5.25		55,688		2/7/2018
Settlement warrants		8/16/2016		40,000	$	3.75		40,000		8/16/2021
Warrants issued to investor relations consultant		7/19/2013		60,000	$	8.50		60,000		7/19/2018
Placement Agent Warrants		12/27/2016		210,313	$	1.79		-		12/27/2019
PIPE Investor Warrants		12/27/2016		5,257,828	$	1.79		-		12/27/2019
				5,748,829	$	1.91		280,688

- Definition

The entire disclosure for shareholders' equity comprised of portions attributable to the parent entity and noncontrolling interest, including other comprehensive income. Includes, but is not limited to, balances of common stock, preferred stock, additional paid-in capital, other capital and retained earnings, accumulated balance for each classification of other comprehensive income and amount of comprehensive income.

+ References

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+ Details

Derivative Instruments

12 Months Ended

Dec. 31, 2016

Derivative Instruments and Hedging Activities Disclosure [Abstract]

Derivative Instruments

NOTE 13. DERIVATIVE INSTRUMENTS

During the year ended December 31, 2016, the Company modified certain common stock purchase warrants issued in conjunction with debt which are detachable, or free standing, instruments. The warrants were considered a derivative liability upon modification and the estimated fair value of the warrants was reclassified from equity to liabilities. In addition, the Company recorded a derivative liability and debt discount associated with the estimated fair value of the embedded conversion feature in the Convertible Note (see Note 10). Both instruments contained a provision which allowed for one-time adjustments to their exercise or conversion prices. The one-time adjustment occurred upon the closing of the Company’s underwritten public offering of its common stock (see Note 12), on March 16, 2016, whereby the conversion and exercise prices were adjusted from $5.90 to $3.60 per share. At the time of the one-time adjustment, the Company reclassified the derivative liabilities to equity based on their then estimated fair value at that time. The Company estimated the fair value of the derivative liabilities utilizing Level 3 inputs. The Company used the Black-Scholes-Merton option pricing model as it embodies all of the requisite assumptions (including trading volatility, remaining term to maturity, market price, strike price, and risk-free rates) necessary to value these instruments.

The table below illustrates the fair value per share determined by the Black-Scholes-Merton option pricing model with the following assumptions used for valuing derivative liabilities:

	2016
Expected volatility	103 - 111	%
Risk-free interest rate	1.22 - 1.70	%
Dividend yield	-

The Company estimated the expected terms based on the remaining contractual life of the instruments on the date of the fair value measurement. The warrant expires on May 11, 2025 and the convertible note had an original maturity date of May 11, 2021.

The following table provides a reconciliation of all liabilities measured at fair value using Level 3 significant unobservable inputs:

	September 30, 2016
Warrant derivative liability:
Balance at January 1, 2016	$	-
Modification of warrant and reclassification from equity to liabilities		675
Change in fair value		(211	)
Reclassification from liabilities to equity upon closing of public equity offering		(464	)
Balance at December 31, 2016	$	-

Embedded conversion feature derivative liability:
Balance at January 1, 2016	$	-
Embedded conversion feature in Convertible Note issued		2,322
Change in fair value		324
Reclassification from liabilities to equity upon closing of public equity offering		(2,646	)
Balance at December 31, 2016	$	-

- Definition

The entire disclosure for derivative instruments and hedging activities including, but not limited to, risk management strategies, non-hedging derivative instruments, assets, liabilities, revenue and expenses, and methodologies and assumptions used in determining the amounts.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
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+ Details

Income Taxes

12 Months Ended

Dec. 31, 2016

Income Tax Disclosure [Abstract]

Income Taxes

NOTE 14. INCOME TAXES

The Company is subject to taxation in the United States, California, New Jersey, Texas and Pennsylvania. The provision for income taxes for the years ended December 31, 2016 and 2015 are summarized below:

	December 31, 2016			December 31, 2015
Current:
Federal	$	-		$	-
State		8			5
Total current	$	8		$	5

Deferred:
Federal	$	19,847		$	14,037
State		5,802			4,036
Change in valuation allowance		(25,760	)		(18,072	)
Total deferred		(111	)		-
Income tax provision (benefit)	$	(103	)	$	5

Income taxes for the years ended December 31, 2016 and 2015, are recorded in the general and administrative expenses line item in the accompanying consolidated statements of operations.

A reconciliation of income taxes computed by applying the statutory U.S. income tax rate to the Company’s loss before income taxes to the income tax provision is as follows:

	December 31, 2016			December 31, 2015
U.S. federal statutory tax rate		35.00	%		35.00	%
Benefit of lower tax brackets		(1.00	)%		(1.00	)%
State tax benefit, net		0.08	%		(0.03	)%
Research and development credits		0.00	%		0.00	%
Employee stock based compensation		(1.47	)%		(0.67	)%
Loss on debt conversion		0.00	%		0.00	%
Other		(0.18	)%		(0.71	)%
Valuation allowance		(31.89	)%		(32.62	)%
Effective income tax rate		0.54	%		(0.03	)%

Deferred tax assets and liabilities reflect the net tax effects of temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for income tax purposes. Significant components of the Company’s deferred tax assets are as follows (in thousands):

	December 31, 2016			December 31, 2015
Deferred tax assets (liabilities):
NOL’s	$	21,555		$	15,099
Depreciation and amortization		199			121
Other		398			346
Research & development credits		556			556
Deferred stock compensation		3,875			2,997
Park stock purchase identifiable intangibles		(936	)		(1,047	)
Unrealized gain or loss on investments		-			-
Total deferred tax assets, net		25,647			18,072
Valuation allowance		(26,583	)		(19,119	)
Net deferred tax liabilities	$	(936	)	$	(1,047	)

Realization of deferred tax assets is dependent upon future earnings, if any, the timing and amount of which are uncertain. Accordingly, the net deferred tax assets have been fully offset by a valuation allowance. The valuation allowance increased by approximately $7.4 and $5.2 in 2016 and 2015, respectively.

As of December 31, 2016, the Company had net operating loss carryforwards for federal income tax purposes of approximately $54,275 which expire beginning in the year 2027 and federal research and development tax credits of approximately $354 which expire beginning in the year 2026. As of December 31, 2015, the Company had net operating loss carryforwards for state income tax purposes of approximately $52,334 which expire beginning in the year 2017 and state research and development tax credits of approximately $305 which do not expire.

The deferred tax asset at December 31, 2015 does not include any excess tax benefits from employee stock option exercises and RSU vests that are a component of the federal and California net operating loss carryover, respectively. The Company’s stockholders’ equity balance will be increased if and when such excess tax benefits are ultimately realized.

Utilization of the net operating losses may be subject to substantial annual limitation due to federal and state ownership change limitations provided by the Internal Revenue Code and similar state provisions. Such annual limitations could result in the expiration of the net operating losses ad credits before their utilization.

The Company did not have any unrecognized tax benefits as of December 31, 2016 and 2015, all of which is offset by a full valuation allowance. These unrecognized tax benefits, if recognized, would not affect the effective tax rate.

Employee Savings Plan

12 Months Ended

Dec. 31, 2016

Compensation and Retirement Disclosure [Abstract]

Employee Savings Plan

NOTE 15. EMPLOYEE SAVINGS PLAN

The Company has established an employee savings plan pursuant to Section 401(k) of the Internal Revenue Code, effective January 1, 2014. The plan allows participating employees to deposit into tax deferred investment accounts up to 100% of their salary, subject to annual limits. The Company makes certain matching contributions to the plan in amounts up to 4% of the participants’ annual cash compensation, subject to annual limits. The Company contributed approximately $248 and $146 to the plan during the years ended December 31, 2016 and 2015, respectively.

Commitments and Contingencies

12 Months Ended

Dec. 31, 2016

Commitments and Contingencies Disclosure [Abstract]

Commitments and Contingencies

NOTE 16. COMMITMENTS AND CONTINGENCIES

Contingent Acquisition Obligation

On April 1, 2014, the Company acquired all of the outstanding membership interests of Pharmacy Creations, LLC (“PC”). The sellers of PC, are entitled to receive certain payments, including contingent consideration upon certain conditions, if PC earns revenue of between $3,500 and $7,500 during the 12 month period ending March 31, 2016, an aggregate of that number of shares of Imprimis common stock equal to the amount that such revenue exceeds $3,500 divided by 18.5882, rounded down to the lower whole number (not to exceed 215,190 shares). The estimated fair value of the contingent acquisition obligation was $483 and included in the contingent acquisition obligation in the accompanying balance sheet at December 31, 2015. During May 2016, the Company paid the sellers of PC $100 in cash and 75,000 shares of its common stock with a fair value of $302, as payment in full related to the contingent acquisition obligation. Related to the payment of the contingent acquisition obligation the Company recorded a gain of $81 during the year ended December 31, 2016, which is included in other income, net in the accompanying consolidated statement of operations.

Operating Leases

In June 2014, the Company entered into a lease agreement for 7,565 square feet of office space that commenced on September 1, 2014 and continues until October 31, 2018. Monthly rent began on September 1, 2014 in the amount of $20,426, with a 3% increase in the base rent amount on an annual basis. The lease agreement allows for the monthly rent amount to be abated for two months at various times during the lease agreement.

In January 2015, the Company entered into a commercial lease agreement, for the lease to Park of approximately 4,500 square feet of laboratory and office space. The monthly rent amount is $10 and includes annual increases of approximately 3%. The current lease term expires on December 31, 2020.

In February 2015, the Company entered into a lease agreement for approximately 8,602 square feet of laboratory, warehouse and office space in Roxbury, New Jersey. The current lease term expires on July 31, 2022. The monthly rent amount is $10 and includes annual increases of approximately 3.75%, and the lease allows for the first five months of rent amounts to be abated.

In August 2015, the Company entered into a lease agreement for approximately 1,100 square feet of laboratory, warehouse and office space in Allen, Texas. The lease term expires on October 31, 2019. The monthly rent amount is $3 and includes annual increases of approximately 2%. Subsequent to December 31, 2016, the Company transferred its obligations under the Allen, Texas lease as a part of the Company’s sale of ImprimisRx TX, Inc. (See also Note 18).

Rent expense for the years ended December 31, 2016 and 2015 was $668 and $641, respectively. The following represents future annual minimum lease payments, net of expected sublease income, as of December 31, 2016:

2017	$	495
2018		496
2019		257
2020		266
2021		134
Thereafter		79
Total	$	1,727

Legal

Urigen, et. al, Litigation

On October 2014, the Company entered into a license agreement (the “Urigen License”) with Urigen Pharmaceuticals, Inc. (“Urigen”) for a license of certain U.S. patents and patent applications to develop and sell in the U.S. Urigen’s URG101 product, a heparin and alkalinized lidocaine compounded formulation for the prevention or treatment of disorders of the lower urinary tract. The Company, as the plaintiff, filed a civil action in the San Diego Superior Court against Urigen in December 2015, wherein the Company outlined serious concerns regarding material failures and inaccuracies of the representation and warranties provided by Urigen in the Urigen License, which have affected the Company’s ability to realize the expected benefit of the Urigen License. Urigen filed a cross-complaint in April 2016 for breach of contract asserting unpaid royalties totaling $698 and requesting a decree to cancel the Urigen Agreement. The Company filed another complaint in May 2016 with the U.S. District Court for the Southern District of California for declaratory judgment of the invalidity of the core patent filing related to Urigen’s URG 101. In June 2016, the Company received notice from Urigen of their election to terminate the Urigen License. In November 2016, the Company and Urigen entered into a settlement and mutual release agreement whereby all parties agreed to settle all disputes related to the Urigen License and associated litigation matters, the Company agreed to make a one-time payment to Urigen related to past sales of Urigen’s URG101 product and to cease selling the URG101 product over a certain period of time. The Company recorded a gain related to the settlement with Urigen totaling $551 which is included in other income, net in the accompanying consolidated statement of operations.

Corwin, Kammer, et. al. Litigation

In February 2014, Robert Kammer (“Kammer”), the Company’s Chairman of the Board, filed a lawsuit in the San Diego Superior Court against Merlyn Corwin (“Corwin”) to enforce his contract rights related to a settlement agreement the parties had previously entered into involving shares of the Company’s common stock. Corwin filed an answer to the complaint in March 2014 and in June 2014 filed the first amended cross complaint adding the Company as a cross-defendant. In August 2014, Corwin filed a seconded amended cross complaint (the “SACC”) which added Mark Baum (“Baum”), the Company’s Chief Executive Officer, and an individual who previously provided consulting services to the Company as additional cross-defendants. The SACC alleged numerous causes of action including securities fraud, concealment, misrepresentations, inducement of misrepresentations, rescission – undue influence, intentional infliction of emotional distress and declaratory relief of invalidity of the settlement agreement. In September 2014, the Company and Baum filed an anti-strategic lawsuit against public participation motion (“Anti-SLAPP”), arguing all allegations in the SACC were based on protected activity under the litigation privilege. Kammer also filed an Anti-SLAPP motion in October 2014. In November 2014, the Company, Baum and Kammer were granted both Anti-SLAPP motions, with the ruling judge deciding that the parties successfully demonstrated that the allegations arose from activity protected by the litigation privilege. The judge further found that the evidence Corwin relied upon in her arguments failed to demonstrate a probability that she could prevail on any of the claims. The court then ordered Corwin to pay the Company’s and Baum’s attorney fees and the case was dismissed. In May 2015, Corwin filed an appeal and in November 2015, the appellate court reversed the Anti-SLAPP decision of the trial court. In April 2016, the Company and Baum filed a demurrer to the SACC. The court ordered a ruling on the demurrer in June 2016, dismissing most of the causes of action against Baum and the Company, but leaving the claim for fraud by concealment and intentional infliction of emotional distress. In August 2016, all parties related to this litigation entered into a settlement and mutual release agreement, whereby all parties agreed to settle all disputes and release one another of any legal claims. The Company issued 40,000 at-the-money warrants (see Note 12) as part of the settlement consideration. The estimated fair value of the warrant (see Note 12) and associated legal expenses were recorded in general and administrative expenses during the year ended December 31, 2016 in the accompanying consolidated statement of operations.

General and Other

In the ordinary course of business, the Company may face various claims brought by third parties and the Company may, from time to time, make claims or take legal actions to assert the Company’s rights, including intellectual property disputes, contractual disputes and other commercial disputes. Any of these claims could subject the Company to litigation. Management believes the outcomes of currently pending claims are not likely to have a material effect on the Company’s consolidated financial position and results of operations.

Indemnities

In addition to the indemnification provisions contained in the Company’s charter documents, the Company generally enters into separate indemnification agreements with each of the Company’s directors and officers. These agreements require the Company, among other things, to indemnify the director or officer against specified expenses and liabilities, such as attorneys’ fees, judgments, fines and settlements, paid by the individual in connection with any action, suit or proceeding arising out of the individual’s status or service as the Company’s director or officer, other than liabilities arising from willful misconduct or conduct that is knowingly fraudulent or deliberately dishonest, and to advance expenses incurred by the individual in connection with any proceeding against the individual with respect to which the individual may be entitled to indemnification by the Company. The Company also indemnifies its lessors in connection with its facility leases for certain claims arising from the use of the facilities. These indemnities do not provide for any limitation of the maximum potential future payments the Company could be obligated to make. Historically, the Company has not incurred any payments for these obligations and, therefore, no liabilities have been recorded for these indemnities in the accompanying consolidated balance sheets.

Insurance Claims

In June 2016, the Company’s Texas based facility was damaged related to a malfunction with the property’s sprinkler system. The Company commenced restoration efforts and filed claims for damages under its insurance policies, including claims related to business interruption. During the year ended December 31, 2016, the Company recorded the insurance claim of $861 in other income, net in the accompanying consolidated statement of operations which reflected amounts paid by its insurance carrier related to the claims filed for property damage and business interruption.

PCCA Commission Agreement

On December 21, 2015, the Company entered into a Commission Agreement (the “PCCA Commission Agreement) with Professional Compounding Centers of America, Inc. (“PCCA”). The PCCA Commission Agreement replaces a Strategic Alliance Agreement (the “PCCA Strategic Alliance Agreement”) entered into on February 18, 2013 and a License Agreement (the “PCCA License Agreement) entered into on August 30, 2012, in each case between the Company and PCCA. Upon the execution of the PCCA Commission Agreement, the Company and PCCA mutually agreed to terminate the PCCA Strategic Alliance Agreement and PCCA License Agreement. No amounts were due or paid under either the PCCA Strategic Alliance Agreement or PCCA License Agreement.

PCCA has previously introduced to the Company certain PCCA members, which led to the Company’s acquisition of certain intellectual property (the “PCCA Member IP”) from such PCCA members. Under the terms of the PCCA Strategic Alliance Agreement, PCCA had the right to receive certain commissions based on the Company’s net sales, if any, of any products utilizing the PCCA Member IP. The primary purpose of the PCCA Commission Agreement is to specifically identify the PCCA Member IP subject to this arrangement and to revise the terms and the amount of the commission payments. As a result, pursuant to the terms of the PCCA Commission Agreement, PCCA continues to hold its right to receive commissions based on the Company’s net sales, if any, of any products utilizing the PCCA Member IP. No commission amounts were paid or accrued under this agreement for the years ended December 31, 2016 and 2015.

Asset Purchase Agreements

The Company has acquired intellectual property rights related to certain proprietary innovations from certain inventors (the “Inventors”) through multiple asset purchase agreements. The asset purchase agreements provide that the Inventors will cooperate with the Company in obtaining patent protection for the acquired intellectual property and that the Company will use commercially reasonable efforts to research, develop and commercialize a product based on the acquired intellectual property. In addition, the Company has acquired a right of first refusal on additional intellectual property and drug development opportunities presented by these Inventors.

In consideration for the acquisition of the intellectual property rights, the Company is obligated to make payments to the Inventors based on the completion of certain milestones, generally consisting of: (1) a payment payable within 30 days after the issuance of the first patent in the United States arising from the acquired intellectual property (if any); (2) a payment payable within 30 days after the Company files the first investigational new drug application (“IND”) with the FDA for the first product arising from the acquired intellectual property (if any); (3) for certain of the Inventors, a payment payable within 30 days after the Company files the first new drug application with the FDA for the first product arising from the acquired intellectual property (if any); and (4) certain royalty payments based on the net receipts received by the Company in connection with the sale or licensing of any product based on the acquired intellectual property (if any), after deducting (among other things) the Company’s development costs associated with such product. If, following five years after the date of the applicable asset purchase agreement, the Company either (a) for certain of the Inventors, has not filed an IND or, for the remaining Inventors, has not initiated a study where data is derived, or (b) has failed to generate royalty payments to the Inventors for any product based on the acquired intellectual property, the Inventors may terminate the applicable asset purchase agreement and request that the Company re-assign the acquired technology to the Inventors. $3 and $0 were accrued under these agreements for royalty expenses during the years ended December 31, 2016 and 2015, respectively.

Segment Information and Concentrations

12 Months Ended

Dec. 31, 2016

Segment Reporting [Abstract]

Segment Information and Concentrations

NOTE 17. SEGMENT INFORMATION AND CONCENTRATIONS

The Company operates the business on the basis of a single reportable segment, which is the business of developing proprietary drug therapies and providing such therapies through sterile and non-sterile pharmaceutical compounding services. The Company’s chief operating decision-maker is the Chief Executive Officer, who evaluates the Company as a single operating segment.

The Company categorizes revenues by geographic area based on selling location. All operations are currently located in the United States; therefore, total revenues for 2016 and 2015 are attributed to the United States. All long-lived assets at December 31, 2016 and 2015 are located in the United States.

The Company sells its compounded formulations to a large number of customers. No single customer contributed 10% or more of the Company’s total pharmacy sales in the years ended December 31, 2016 and 2015.

The Company receives its active pharmaceutical ingredients from two and three main supplier during the years ended December 31, 2016 and 2015, respectively. These suppliers collectively accounted for 63% and 43% of drug and chemical purchases during the years ended December 31, 2016 and 2015, respectively.

- Definition

The entire disclosure for reporting segments including data and tables. Reportable segments include those that meet any of the following quantitative thresholds a) it's reported revenue, including sales to external customers and intersegment sales or transfers is 10 percent or more of the combined revenue, internal and external, of all operating segments b) the absolute amount of its reported profit or loss is 10 percent or more of the greater, in absolute amount of 1) the combined reported profit of all operating segments that did not report a loss or 2) the combined reported loss of all operating segments that did report a loss c) its assets are 10 percent or more of the combined assets of all operating segments.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 34
-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e8981-108599

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 41
-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e9038-108599

Reference 3: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
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-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e8971-108599

Reference 4: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
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Reference 5: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
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Reference 6: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
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Reference 7: http://www.xbrl.org/2003/role/presentationRef
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-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e8844-108599

Reference 8: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
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Reference 9: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
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-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e9031-108599

Reference 10: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 42
-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e9054-108599

Reference 11: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
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Reference 12: http://www.xbrl.org/2003/role/presentationRef
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Reference 13: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
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-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e8924-108599

Reference 14: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
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-Paragraph 30
-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e8906-108599

+ Details

Subsequent Events

12 Months Ended

Dec. 31, 2016

Subsequent Events [Abstract]

Subsequent Events

NOTE 18. SUBSEQUENT EVENTS

The Company has performed an evaluation of events occurring subsequent to December 31, 2016 through the filing date of this Annual Report on Form 10-K (the “Annual Report”). Based on its evaluation, nothing other than the events described below needs to be disclosed.

In February 2017, the Company entered into a Stock Purchase Agreement (the “TX SPA”) with Livernois & London, LLC (“Livernois”). Pursuant to the terms of the TX SPA, the Company sold to Livernois and Livernois purchased from the Company one hundred percent (100%) of the issued and outstanding shares of common stock of the Company’s Texas based subsidiary, ImprimisRx TX, Inc. dba ImprimisRx (“Imprimis TX”). The Company ceased operations of Imprimis TX in 2016 and the Agreement does not transfer to Livernois any Company rights to intellectual property, products, clients, nor any existing Company business operations. As consideration for the purchase of Imprimis TX, Livernois paid the Company $10 and the Company assigned, and Livernois assumed, the remaining lease obligation totaling approximately $113 for its Texas based facility. ImprimisRx TX did not have significant operation and as such, the closure and selling of the subsidiary is not presented as discontinued operations.

Summary of Significant Accounting Policies (Policies)

12 Months Ended

Dec. 31, 2016

Accounting Policies [Abstract]

Basis of Presentation

Basis of Presentation

Use of Estimates

Use of Estimates

Liquidity

Liquidity

Revenue Recognition and Deferred Revenue

Revenue Recognition and Deferred Revenue

Product Revenues

License Revenues

Cost of Sales

Cost of Sales

Research and Development

Research and Development

Debt Issuance Costs and Debt Discount

Debt Issuance Costs and Debt Discount

Intellectual Property

Intellectual Property

Income Taxes

Income Taxes

Cash and Cash Equivalents

Cash and Cash Equivalents

Cash equivalents include short-term, highly liquid investments with maturities of three months or less at the time of acquisition.

Concentrations of Credit Risk

Concentrations of Credit Risk

Accounts Receivable

Accounts Receivable

Inventories

Inventories

Property, Plant and Equipment

Property, Plant and Equipment

Business Combinations

Business Combinations

	●	future expected cash flows from product sales, support agreements, consulting contracts, other customer contracts, and acquired developed technologies and patents; and

	●	discount rates utilized in valuation estimates.

Goodwill and Intangible Assets

Goodwill and Intangible Assets

	●	significant underperformance of the Company’s business relative to expected operating results;

	●	significant adverse economic and industry trends;

	●	significant decline in the Company’s market capitalization for an extended period of time relative to net book value; and

	●	expectations that a reporting unit will be sold or otherwise disposed.

The goodwill impairment test consists of a two-step process as follows:

Impairment of Long-Lived Assets

Impairment of Long-Lived Assets

Third Party Billing and Collection Agreements

Third Party Billing and Collection Agreements

Deferred Rent

Deferred Rent

Fair Value Measurements

Fair Value Measurements

●	Level 1: Applies to assets or liabilities for which there are quoted prices (unadjusted) for identical assets or liabilities in active markets. A quoted price in an active market provides the most reliable evidence of fair value and must be used to measure fair value whenever available.

●	Level 2: Applies to assets or liabilities for which there are significant other observable inputs other than Level 1 prices, such as quoted prices for similar assets or liabilities; quoted prices in markets that are not active; or other inputs that are observable or can be corroborated by observable market data.

●	Level 3: Applies to assets or liabilities for which there are significant unobservable inputs that reflect a reporting entity’s own assumptions about the assumptions that market participants would use in pricing an asset or liability. For example, Level 3 inputs would relate to forecasts of future earnings and cash flows used in a discounted future cash flows method.

Derivative Instruments

Derivative Instruments

Stock-Based Compensation

Stock-Based Compensation

Basic and Diluted Net Loss per Common Share

Basic and Diluted Net Loss per Common Share

The following table shows the computation of basic and diluted net loss per share of common stock for the years ended December 31, 2016 and 2015:

	For the			For the
	Year Ended			Year Ended
	December 31, 2016			December 30, 2015

Numerator – net loss	$	(19,087	)	$	(15,899	)
Denominator – weighted average number of shares outstanding, basic and diluted		12,743,184			9,576,142
Net loss per share, basic and diluted	$	(1.50	)	$	(1.66	)

Recently Adopted Accounting Pronouncements

Recently Adopted Accounting Pronouncements

Recently Issued Accounting Pronouncements

Recently Issued Accounting Pronouncements

Summary of Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2016

Accounting Policies [Abstract]

Schedule of Basic and Diluted Earnings Per Common Share

The following table shows the computation of basic and diluted net loss per share of common stock for the years ended December 31, 2016 and 2015:

	For the			For the
	Year Ended			Year Ended
	December 31, 2016			December 30, 2015

Numerator – net loss	$	(19,087	)	$	(15,899	)
Denominator – weighted average number of shares outstanding, basic and diluted		12,743,184			9,576,142
Net loss per share, basic and diluted	$	(1.50	)	$	(1.66	)

Acquisitions (Tables) - Acquisition of Park [Member]

12 Months Ended

Dec. 31, 2016

Schedule of Acquisition Date Fair Value of Consideration

The total acquisition date fair value of consideration transferred and to be transferred is estimated as follows:

Cash payment to Sellers at closing	$	3,100
Restricted common stock issuance to Sellers at closing		425
Deferred tax liability		1,047
Deferred consideration to Sellers		591
Total acquisition date fair value	$	5,163

Schedule of Estimated Fair Value of Assets Acquired and Liabilities Assumed

The following table summarizes the estimated fair values of the assets acquired and liabilities assumed at the acquisition date.

Cash and cash equivalents	$	95
Accounts receivable		399
Inventories		232
Furniture and equipment		252
Intangible assets		2,629
Total identifiable assets acquired		3,607
Accounts payable and accrued expenses		304
Other liabilities		35
Total liabilities assumed		339
Total identifiable assets less liabilities assumed		3,268
Goodwill		1,895
Net assets acquired	$	5,163

Schedule of Result of Operation from Acquisition

The amount of revenues and net income of Park included in the Company’s consolidated statement of operations from the acquisition date through the period ended December 31, 2015 are as follows:

Total revenues		$	6,134
Net income		$	1,088

Schedule of Intangible Assets Acquisition

The following table sets forth the components of identified intangible assets associated with the Park Acquisition and their estimated useful lives.

	Fair Value		Useful Life
Customer relationships	$	2,387		3 - 15 years
Trade name		10		5 years
Non-competition clause		224		3 years
State pharmacy licenses		8		25 years
	$	2,629

Inventories (Tables)

12 Months Ended

Dec. 31, 2016

Inventory Disclosure [Abstract]

Schedule of Inventories

The composition of inventories, net of reserve, as of December 31, 2016 and 2015 was as follows:

	December 31, 2016		December 31, 2015
Raw materials	$	669	$	775
Finished goods		1,172		637
Total inventories	$	1,841	$	1,412

Prepaid Expenses and Other Current Assets (Tables)

12 Months Ended

Dec. 31, 2016

Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Abstract]

Schedule of Prepaid Expenses and Other Current Assets

Prepaid expenses and other current assets at December 31, 2016 and 2015 consisted of the following:

	December 31, 2016		December 31, 2015
Prepaid insurance	$	315	$	297
Other prepaid expenses		517		370
Deposits and other current assets		106		119
Total prepaid expenses and other current assets	$	938	$	786

Property, Plant and Equipment (Tables)

12 Months Ended

Dec. 31, 2016

Property, Plant and Equipment [Abstract]

Schedule of Property, Plant and Equipment

Property, plant and equipment at December 31, 2016 and 2015 consisted of the following:

	December 31, 2016			December 31, 2015
Property, plant and equipment, net:
Computer software and hardware	$	831		$	323
Furniture and equipment		424			350
Lab and pharmacy equipment		2,559			538
Leasehold improvements		4,836			1,746
		8,650			2,957
Accumulated depreciation and amortization		(1,355	)		(300	)
	$	7,295		$	2,657

Intangible Assets and Goodwill (Tables)

12 Months Ended

Dec. 31, 2016

Goodwill and Intangible Assets Disclosure [Abstract]

Schedule of Intangible Assets

The Company’s intangible assets at December 31, 2016 consisted of the following:

	Amortization
	periods			Accumulated						Net
	(in years)	Cost		amortization			Impairment			Carrying value
Patents	17-19 years	$	214	$	(6	)	$	-		$	208
Trademarks	Indefinite		224		-			-			224
Customer relationships	3-15 years		2,998		(554	)		(15	)		2,429
Trade name	5 years		16		(7	)		(1	)		8
Non-competition clause	3-4 years		294		(184	)		(20	)		90
State pharmacy licenses	25 years		45		(4	)		(28	)		13
		$	3,791	$	(755	)	$	(64	)	$	2,972

The Company’s intangible assets at December 31, 2015 consisted of the following:

	Amortization
	periods			Accumulated			Net
	(in years)	Cost		amortization			Carrying value
Patents	17-19 years	$	64	$	(1	)	$	63
Trademarks	Indefinite		121		-			121
Customer relationships	3-15 years		2,998		(297	)		2,701
Trade name	5 years		16		(4	)		12
Non-competition clause	3-4 years		294		(99	)		195
State pharmacy licenses	25 years		45		(2	)		43
		$	3,538	$	(403	)	$	3,135

Schedule of Amortization Expenses for Intangible Assets

Amortization expense for intangible assets for the years ended December 31, 2016 and 2015 was as follows:

	For the		For the
	Year Ended		Year Ended
	December 31, 2016		December 31, 2015
Patents	$	5	$	1
Customer relationships		255		260
Trade name		3		3
Non-competition clause		86		90
State pharmacy licenses		2		1
	$	351	$	355

Schedule of Estimated Future Amortization Expense

Estimated future amortization expense for the Company’s intangible assets at December 31, 2016 is as follows:

Years ending December 31,
2017	$	359
2018		218
2019		215
2020		212
2021		212
Thereafter		1,755
	$	2,972

Schedule of Goodwill

The changes in the carrying value of the Company’s goodwill during the years ended December 31, 2016 and 2015 were as follows:

Balance at January 1, 2015	$	332
Acquisition of Park (see Note 3)		1,895
Acquisition of CAP (see Note 3)		239
Balance at December 31, 2015		2,466
Impairment of CAP (see Note 2)		(239	)
Balance at December 31, 2016	$	2,227

Accounts Payable and Accrued Expenses (Tables)

12 Months Ended

Dec. 31, 2016

Payables and Accruals [Abstract]

Schedule of Accounts Payable and Accrued Expenses

Accounts payable and accrued expenses at December 31, 2016 and 2015 consisted of the following:

	December 31, 2016			December 31, 2015
Accounts payable	$	2,999		$	3,185
Deferred rent		412			63
Accrued interest (see Note 10)		116			90
Accrued exit fee for note payable (see Note 10)		667			500
Building lease liability(1)		11			46
Other accrued expenses (2)		-			23
Total accounts payable and accrued expenses		4,205			3,907
Less: Current portion		(3,538	)		(3,407	)
Non-current total accrued expenses	$	667		$	500

	(1)	In September 2014, the Company relocated its primary operations to a 7,565 square foot office facility in San Diego, California. In February 2015, the Company entered into a sublease agreement to sublet 3,874 square feet of its previously occupied offices through the remaining term of the lease at a monthly rent amount of $8. The Company recognized a loss of approximately $117 during the year ended December 31, 2014 related to the estimated remaining lease liability, net of expected sublease income, of the previously occupied offices. In September 2016, the Company decided to cease operations at its Texas location and started steps to wind down operations. The Company recognized a loss of $16 during the year ended December 31, 2016 related to the estimated remaining lease liability. The obligations were discounted based on current prevailing market rates.

	(2)	The amount consists of a $23 stock-based compensation accrual at December 31, 2015, for stock options to be granted for services performed. The stock-based compensation expense related to the accruals was $23 during the year ended December 31, 2015. The $23 was recorded to additional paid-in-capital upon issuance of the stock options in 2016.

Debt (Tables)

12 Months Ended

Dec. 31, 2016

Debt Disclosure [Abstract]

Summary of Notes Payable

Notes payable at December 31, 2016 were as follows:

	December 31, 2016
December 2016 Amended Note	$	13,332
Less: Discount on notes		(1,422	)
Less: Current portion		(4,999	)
Long-term portion	$	6,911

Summary of Future Minimum Payments

Future minimum payments under notes payable outstanding at December 31, 2016 are as follows:

Year Ending December 31, 2016	Amount
2017	$	6,485
2018		8,905
Total minimum payments		15,390
Less: amount representing interest		(2,058	)
Notes payable, gross		13,332
Less: unamortized discount		(1,422	)
Note payable, net of unamortized debt discount	$	11,910

Capital Lease Obligation (Tables)

12 Months Ended

Dec. 31, 2016

Leases [Abstract]

Schedule of Future Payment Under Capital Lease

At December 31, 2016, future payments under the Company’s capital lease were as follows:

	Amount
2017	$	773
2018		773
2019		751
Total minimum lease payments		2,298
Less: amount representing interest payments		(244	)
Present value of future minimum lease payments		2,053
Less: unamortized discount		(277	)
		1,776
Less: current portion, net of unamortized discount		(458	)
Capital lease obligation, net of current portion and unamortized discount	$	1,318

Stockholders' Equity (Deficit) and Stock-Based Compensation (Tables)

12 Months Ended

Dec. 31, 2016

Schedule of Stock Option Plan Activity

A summary of the stock option activity under the Plan for the year ended December 31, 2016 is as follows:

	Number of shares			Weighted Avg. Exercise Price		Weighted Avg. Remaining Contractual Life		Aggregate Intrinsic Value
Options outstanding - January 1, 2016		1,544,026		$	5.74
Options granted		549,350		$	3.99
Options exercised		(15,000	)	$	3.68
Options cancelled/forfeit		(65,063	)	$	7.80
Options outstanding - December 31, 2016		2,013,313			6.20		6.28	$	13
Options exercisable		808,067			6.18		5.75	$	13
Options vested and expected to vest		1,892,790			6.20		6.10	$	13

Schedule of Market-based Vesting Conditions for Stock Option Units Granted

These market-based vesting conditions are as follows:

Tranche	Number of Shares	Target Share Price
Tranche 1	200,000 shares	$9.00 or greater
Tranche 2	100,000 shares	$10.00 or greater
Tranche 3	100,000 shares	$12.00 or greater
Tranche 4	100,000 shares	$14.00 or greater
Tranche 5	100,000 shares	$15.00 or greater

Schedule of Fair Value Assumption

	2016			2015
Weighted-average fair value of options granted	$	3.91		$	6.22
Expected terms (in years)		5.81 - 6.11			5.81 - 6.11
Expected volatility		101 - 112	%		101 - 121	%
Risk-free interest rate		1.07 - 1.70	%		1.39 - 1.68	%
Dividend yield		-			-

The table below illustrates the fair value per share determined using the Black-Scholes-Merton option pricing model with the following assumptions used for valuing options granted to consultants:

	2016			2015
Weighted-average fair value of options granted	$	6.18		$	6.49
Expected terms (in years)		10			10
Expected volatility		109	%		108 - 109	%
Risk-free interest rate		1.06	%		1.06 - 1.63	%
Dividend yield		-			-

Schedule of Shares Outstanding and Exercisable

The following table summarizes information about stock opt0ions outstanding and exercisable at December 31, 2016:

	Options Outstanding						Options Exercisable
			Weighted
			Average		Weighted				Weighted
			Remaining		Average				Average
	Number		Contractual		Exercise		Number		Exercise
Range of Exercise Prices	Outstanding		Life in Years		Price		Exercisable		Price
$2.40 - $2.60		147,000		5.80	$	2.43		125,000	$	2.40
$3.74 - $4.50		695,623		7.69	$	4.05		225,256	$	4.25
$5.49 - $7.99		952,103		5.01	$	7.54		249,857	$	6.83
$8.06 - $8.99		213,557		6.10	$	8.92		202,924	$	8.95
$42.80		5,030		3.87	$	42.80		5,030	$	42.80
		2,013,313		6.28	$	6.20		808,067	$	6.18

Schedule of Market-based Vesting Conditions for Restricted Stock Units Granted

The market-based vesting conditions applicable to the Boll Performance Equity Award are as follows:

Tranche	Number of Shares	Target Share Price
Tranche 1	30,000 shares	$10.00 or greater
Tranche 2	30,000 shares	$15.00 or greater
Tranche 3	30,000 shares	$20.00 or greater
Tranche 4	30,000 shares	$25.00 or greater
Tranche 5	37,500 shares	$30.00 or greater

Schedule of Assumptions Used

The Company used a lattice binomial model to estimate a derived service period of 33 months related to the performance-based vesting grants and used the following assumptions:

	2016
Market price	$	3.98
Contractual terms (in years)		5.00
Expected volatility		102	%
Risk-free interest rate		1.04	%
Dividend yield		-

Schedule of Restricted Stock Units Activity

A summary of the Company’s RSU activity and related information for the year ended December 31, 2016 is as follows:

	Number of RSUs			Weighted Average Grant Date Fair Value
RSUs unvested - January 1, 2016		1,487,961		$	3.18
RSUs granted		1,270,950		$	2.25
RSUs vested		(249,018	)	$	8.32
RSUs cancelled/forfeit		(1,217,017	)	$	1.95
RSUs unvested at December 31, 2016		1,292,876		$	2.43

Schedule of Stock Based Compensation Granted to Employees Directors Consultants

	For the		For the
	Year Ended		Year Ended
	December 31, 2016		December 30, 2015
Employees - selling and marketing	$	498	$	370
Employees - general and administrative		2,954		2,720
Directors - general and administrative		221		268
Consultants - selling and marketing		-		83
Other - general and administrative		115		-
Total	$	3,788	$	3,441

Schedule of Warrants Activity

A summary of warrant activity during the year ended December 31, 2016 is as follows:

	Number of Shares Subject to Warrants Outstanding		Weighted Avg. Exercise Price

Warrants outstanding - January 1, 2016		240,688	$	7.41
Granted		5,508,141	$	1.80
Exercised		-
Expired		-
Warrants outstanding and exercisable - December 31, 2016		5,748,829	$	1.91
Weighted average remaining contractual life of the outstanding warrants in years - December 31, 2016		3.08

Schedule of Warrants Outstanding and Warrants Exercisable

All warrants outstanding as of December 31, 2016 are included in the following table:

	Warrants Outstanding						Warrants Exercisable
			Warrants		Exercise		Warrants		Expiration
Warrant Series	Issue Date		Outstanding		Price		Exercisable		Date
Lender warrants (see Note 10)		5/11/2015		125,000	$	1.79		125,000		5/11/2025
Underwriter warrants		2/7/2013		55,688	$	5.25		55,688		2/7/2018
Settlement warrants		8/16/2016		40,000	$	3.75		40,000		8/16/2021
Warrants issued to investor relations consultant		7/19/2013		60,000	$	8.50		60,000		7/19/2018
Placement Agent Warrants		12/27/2016		210,313	$	1.79		-		12/27/2019
PIPE Investor Warrants		12/27/2016		5,257,828	$	1.79		-		12/27/2019
				5,748,829	$	1.91		280,688

Warrant [Member]

Schedule of Fair Value Assumption

	2016
Weighted-average fair value of warrants granted		2.88
Expected terms (in years)		5
Expected volatility		106	%
Risk-free interest rate		0.79	%
Dividend yield		-

Accelerated [Member]

Schedule of Market-based Vesting Conditions for Restricted Stock Units Granted

These market-based accelerated vesting conditions and share amounts (in aggregate) are set forth below:

Tranche	Number of shares	Target share price
Tranche 1	230,000 shares	$9.00 or greater
Tranche 2	230,000 shares	$10.00 or greater
Tranche 3	230,000 shares	$12.00 or greater
Tranche 4	230,000 shares	$14.00 or greater
Tranche 5	287,500 shares	$15.00 or greater

Derivative Instruments (Tables)

12 Months Ended

Dec. 31, 2016

Disclosure of Compensation Related Costs, Share-based Payments [Abstract]

Schedule of Derivative Liabilities at Fair Value

The table below illustrates the fair value per share determined by the Black-Scholes-Merton option pricing model with the following assumptions used for valuing derivative liabilities:

	2016
Expected volatility	103 - 111	%
Risk-free interest rate	1.22 - 1.70	%
Dividend yield	-

Fair Value at Reconciliation of Measured Liabilities

The following table provides a reconciliation of all liabilities measured at fair value using Level 3 significant unobservable inputs:

	September 30, 2016
Warrant derivative liability:
Balance at January 1, 2016	$	-
Modification of warrant and reclassification from equity to liabilities		675
Change in fair value		(211	)
Reclassification from liabilities to equity upon closing of public equity offering		(464	)
Balance at December 31, 2016	$	-

Embedded conversion feature derivative liability:
Balance at January 1, 2016	$	-
Embedded conversion feature in Convertible Note issued		2,322
Change in fair value		324
Reclassification from liabilities to equity upon closing of public equity offering		(2,646	)
Balance at December 31, 2016	$	-

Income Taxes (Tables)

12 Months Ended

Dec. 31, 2016

Income Tax Disclosure [Abstract]

Schedule of Provision for Income Taxes

	December 31, 2016			December 31, 2015
Current:
Federal	$	-		$	-
State		8			5
Total current	$	8		$	5

Deferred:
Federal	$	19,847		$	14,037
State		5,802			4,036
Change in valuation allowance		(25,760	)		(18,072	)
Total deferred		(111	)		-
Income tax provision (benefit)	$	(103	)	$	5

Schedule of Income Tax Reconciliation

A reconciliation of income taxes computed by applying the statutory U.S. income tax rate to the Company’s loss before income taxes to the income tax provision is as follows:

	December 31, 2016			December 31, 2015
U.S. federal statutory tax rate		35.00	%		35.00	%
Benefit of lower tax brackets		(1.00	)%		(1.00	)%
State tax benefit, net		0.08	%		(0.03	)%
Research and development credits		0.00	%		0.00	%
Employee stock based compensation		(1.47	)%		(0.67	)%
Loss on debt conversion		0.00	%		0.00	%
Other		(0.18	)%		(0.71	)%
Valuation allowance		(31.89	)%		(32.62	)%
Effective income tax rate		0.54	%		(0.03	)%

Schedule of Deferred Tax Assets and Liabilities

	December 31, 2016			December 31, 2015
Deferred tax assets (liabilities):
NOL’s	$	21,555		$	15,099
Depreciation and amortization		199			121
Other		398			346
Research & development credits		556			556
Deferred stock compensation		3,875			2,997
Park stock purchase identifiable intangibles		(936	)		(1,047	)
Unrealized gain or loss on investments		-			-
Total deferred tax assets, net		25,647			18,072
Valuation allowance		(26,583	)		(19,119	)
Net deferred tax liabilities	$	(936	)	$	(1,047	)

Commitments and Contingencies (Tables)

12 Months Ended

Dec. 31, 2016

Compensation and Retirement Disclosure [Abstract]

Schedule of Future Payments Under Leases

The following represents future annual minimum lease payments, net of expected sublease income, as of December 31, 2016:

2017	$	495
2018		496
2019		257
2020		266
2021		134
Thereafter		79
Total	$	1,727

Summary of Significant Accounting Policies (Details Narrative) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015
Net loss	$ 19,087	$ 15,899
Accumulated deficit	76,851	57,764
Net cash used in operating activities	11,215	11,143
Cash resources and restricted investments	9,053
Deposit coverage limits by FDIC, per owner	250
Cash deposits in excess of FDIC limits	8,800
Accounts receivable, net of allowance for doubtful accounts	$ 422	$ 180
Property plant and equipment useful life	3 years	5 years
Impairment of long-lived assets	$ 303
Restricted Stock Units [Member]
Number of shares vested during the period	80,245	55,824
Deferred Acquisition Obligations, Stock Options, Unvested RSUs and Warrants [Member]
Anti dilutive securities	9,162,259	3,313,169
Billing and Collection Agreement [Member] \| Third Party [Member]
Percentage of billing and collection amount	55.00%
Billing and collection management expense	$ 55	$ 142
Due to related party	73	$ 81
Intangible Assets [Member]
Impairment of long-lived assets	64
Goodwill [Member]
Impairment of long-lived assets	$ 239
Patents [Member]
Patent estimated useful life	20 years

Summary of Significant Accounting Policies - Schedule of Basic and Diluted Earnings Per Common Share (Details) - USD ($) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015
Accounting Policies [Abstract]
Numerator - net loss	$ (19,087)	$ (15,899)
Denominator - weighted average number of shares outstanding, basic and diluted	12,743,184	9,576,142
Net loss per share, basic and diluted	$ (1.50)	$ (1.66)

Acquisitions (Details Narrative) - USD ($) $ in Thousands	12 Months Ended
Acquisitions (Details Narrative) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Cash payment		$ 421
Goodwill	2,227	$ 2,466	$ 332
Park [Member]
Cash paid for business acquisition, net of fees	3,000
Payment of cash remaining in bank account	100
Total acquisition date fair value	5,163
Acquisition adjusted description		Acquisition was adjusted from 25% to 15%
Increase of goodwill		$ 46
Increase of intangible assets		4
Goodwill	1,895
Net tangible assets	252
Identifiable intangible assets	2,629
Acquisition expenses	201
Park [Member] \| Sellers [Member]
Cash paid for business acquisition, net of fees	638
Cash payment	53
Issuance of common stock for payment	$ 319
Issuance of common stock shares for payment	6,749
Deferred tax liability	$ 1,047
Deferred acquisition obligations	$ 591
Park [Member] \| Restricted Stock [Member]
Number of common stock shares sold	63,525
Number of common stock sold	$ 500
Percentage of discount rate	15.00%
Other 2015 Acquisitions [Member]
Cash payment		945
Goodwill		239
Net tangible assets		641
Identifiable intangible assets		65
Acquisition expenses		$ 135

Acquisitions - Schedule of Acquisition Date Fair Value of Consideration (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015
Cash payment to Sellers at closing		$ 3,005
Park [Member]
Cash payment to Sellers at closing	3,100
Restricted common stock issuance to Sellers at closing	425
Deferred tax liability	1,047
Deferred consideration to Sellers	591
Total acquisition date fair value	$ 5,163

Acquisitions - Schedule of Estimated Fair Value of Assets Acquired and Liabilities Assumed (Details) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Goodwill	$ 2,227	$ 2,466	$ 332
Park [Member]
Cash and cash equivalents	95
Accounts receivable	399
Inventories	232
Furniture and equipment	252
Intangible assets	2,629
Total identifiable assets acquired	3,607
Accounts payable and accrued expenses	304
Other liabilities	35
Total liabilities assumed	339
Total identifiable assets less liabilities assumed	3,268
Goodwill	1,895
Net assets acquired	$ 5,163

Acquisitions - Schedule of Result of Operation from Acquisition (Details) - Park [Member] $ in Thousands	12 Months Ended
	Dec. 31, 2016 USD ($)
Total revenues	$ 6,134
Net income	$ 1,088

Acquisitions - Schedule of Intangible Assets Acquisition (Details) - Park [Member] $ in Thousands	12 Months Ended
	Dec. 31, 2016 USD ($)
Intangible Assets Fair Value	$ 2,629
Customer Relationships [Member]
Intangible Assets Fair Value	$ 2,387
Customer Relationships [Member] \| Minimum [Member]
Useful Life	3 years
Customer Relationships [Member] \| Maximum [Member]
Useful Life	15 years
Trade Name [Member]
Intangible Assets Fair Value	$ 10
Useful Life	5 years
Non-Competition Clause [Member]
Intangible Assets Fair Value	$ 224
Useful Life	3 years
State Pharmacy Licenses [Member]
Intangible Assets Fair Value	$ 8
Useful Life	25 years

Restricted Cash and Short-Term Investments (Details Narrative) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Cash and Cash Equivalents [Abstract]
Certificate of deposit	$ 200	$ 150

Inventories - Schedule of Inventories (Details) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Inventory Disclosure [Abstract]
Raw materials	$ 669	$ 775
Finished goods	1,172	637
Total inventories	$ 1,841	$ 1,412

Prepaid Expenses and Other Current Assets - Schedule of Prepaid Expenses and Other Current Assets (Details) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Abstract]
Prepaid insurance	$ 315	$ 297
Other prepaid expenses	517	370
Deposits and other current assets	106	119
Total prepaid expenses and other current assets	$ 938	$ 786

Property, Plant and Equipment (Details Narrative) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015
Property, Plant and Equipment [Abstract]
Depreciation and amortization of property, plant and equipment	$ 1,055	$ 255

Property, Plant and Equipment - Schedule of Property, Plant and Equipment (Details) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Property, Plant and Equipment [Abstract]
Computer software and hardware	$ 831	$ 323
Furniture and equipment	424	350
Lab and pharmacy equipment	2,559	538
Leasehold improvements	4,836	1,746
Furniture and equipment, gross	8,650	2,957
Accumulated depreciation and amortization	(1,355)	(300)
Furniture and equipment, Net	$ 7,295	$ 2,657

Intangible Assets and Goodwill - Schedule of Intangible Assets (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015
Cost	$ 3,791	$ 3,538
Accumulated amortization	(755)	(403)
Impairment	(64)
Net Carrying value	$ 2,972	3,135
Patents [Member]
Amortization periods (in years)	20 years
Cost	$ 214	64
Accumulated amortization	(6)	(1)
Impairment
Net Carrying value	$ 208	$ 63
Patents [Member] \| Minimum [Member]
Amortization periods (in years)	17 years	17 years
Patents [Member] \| Maximum [Member]
Amortization periods (in years)	19 years	19 years
Trademarks [Member]
Amortization periods description	Indefinite	Indefinite
Cost	$ 224	$ 121
Accumulated amortization
Impairment
Net Carrying value	224	121
Customer Relationships [Member]
Cost	2,998	2,998
Accumulated amortization	(554)	(297)
Impairment	(15)
Net Carrying value	$ 2,429	$ 2,701
Customer Relationships [Member] \| Minimum [Member]
Amortization periods (in years)	3 years	3 years
Customer Relationships [Member] \| Maximum [Member]
Amortization periods (in years)	15 years	15 years
Trade Name [Member]
Amortization periods (in years)	5 years	5 years
Cost	$ 16	$ 16
Accumulated amortization	(7)	(4)
Impairment	(1)
Net Carrying value	8	12
Non-Competition Clause [Member]
Cost	294	294
Accumulated amortization	(184)	(99)
Impairment	(20)
Net Carrying value	$ 90	$ 195
Non-Competition Clause [Member] \| Minimum [Member]
Amortization periods (in years)	3 years	3 years
Non-Competition Clause [Member] \| Maximum [Member]
Amortization periods (in years)	4 years	4 years
State Pharmacy Licenses [Member]
Amortization periods (in years)	25 years	25 years
Cost	$ 45	$ 45
Accumulated amortization	(4)	(2)
Impairment	(28)
Net Carrying value	$ 13	$ 43

Intangible Assets and Goodwill - Schedule of Amortization Expenses for Intangible Assets (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015
Amortization of intangible assets	$ 351	$ 355
Patents [Member]
Amortization of intangible assets	5	1
Customer Relationships [Member]
Amortization of intangible assets	255	260
Trade Name [Member]
Amortization of intangible assets	3	3
Non-Competition Clause [Member]
Amortization of intangible assets	86	90
State Pharmacy Licenses [Member]
Amortization of intangible assets	$ 2	$ 1

Intangible Assets and Goodwill - Schedule of Estimated Future Amortization Expense (Details) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Goodwill and Intangible Assets Disclosure [Abstract]
2017	$ 359
2018	218
2019	215
2020	212
2021	212
Thereafter	1,755
Intangible assets	$ 2,972	$ 3,135

Intangible Assets and Goodwill - Schedule of Goodwill (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015
Intangible Assets And Goodwill - Schedule Of Goodwill Details
Balance beginning	$ 2,466	$ 332
Acquisition of Park (see Note 3)		1,895
Acquisition of CAP (see Note 3)		239
Impairment of CAP (see Note 2)	(239)
Balance ending	$ 2,227	$ 2,466

Accounts Payable and Accrued Expenses - Schedule of Accounts Payable and Accrued Expenses (Details) - USD ($)
$ in Thousands

Dec. 31, 2016

Dec. 31, 2015

Payables and Accruals [Abstract]

Accounts payable

$ 2,999

$ 3,185

Deferred rent

412

Accrued interest (see Note 10)

116

Accrued exit fee for note payable (see Note 10)

667

500

Building lease liability

^[1]

Other accrued expenses

^[2]

Total accounts payable and accrued expenses

4,205

3,907

Less: Current portion

(3,538)

(3,407)

Non-current total accrued expenses

$ 667

$ 500

[1]

In September 2014, the Company relocated its primary operations to a 7,565 square foot office facility in San Diego, California. In February 2015, the Company entered into a sublease agreement to sublet 3,874 square feet of its previously occupied offices through the remaining term of the lease at a monthly rent amount of $8. The Company recognized a loss of approximately $117 during the year ended December 31, 2014 related to the estimated remaining lease liability, net of expected sublease income, of the previously occupied offices. In September 2016, the Company decided to cease operations at its Texas location and started steps to wind down operations. The Company recognized a loss of $16 during the year ended December 31, 2016 related to the estimated remaining lease liability. The obligations were discounted based on current prevailing market rates.

[2]

The amount consists of a $23 stock-based compensation accrual at December 31, 2015, for stock options to be granted for services performed. The stock-based compensation expense related to the accruals was $23 during the year ended December 31, 2015. The $23 was recorded to additional paid-in-capital upon issuance of the stock options in 2016.

Accounts Payable and Accrued Expenses - Schedule of Accounts Payable and Accrued Expenses (Details) (Parenthetical) $ in Thousands	1 Months Ended	12 Months Ended
	Feb. 28, 2015 USD ($) ft²	Dec. 31, 2016 USD ($)	Dec. 31, 2014 USD ($)	Dec. 31, 2015 USD ($)	Sep. 30, 2014 ft²
Payables and Accruals [Abstract]
Area of office space \| ft²					7,565
Area of previous office space \| ft²	3,874
Monthly rent amount	$ 8
Recognized lease losses related to estimated remaining lease liability		$ 16	$ 117
Stock based compensation accrual				$ 23
Additional paid-in-capital		$ 23

Debt (Details Narrative) - USD ($) $ / shares in Units, $ in Thousands			12 Months Ended
	Jan. 22, 2016	May 11, 2015	Dec. 31, 2016	Dec. 31, 2015	Dec. 27, 2016	Mar. 16, 2016
Loan due date			May 11, 2021
Liability of final fee included in accrued expenses			$ 667	$ 500
Fair value of warrants				840
Fair value of contractual term			5 years
Common stock volatility rate			102.00%
Fair value of dividend rate
Fair value of risk-free interest rate			1.04%
Debt discount			$ 970	281
Debt conversion price per share			$ 5.90			$ 5.90
Proceeds from convertible note			$ 2,772
Warrants exercise price per share			$ 1.915			$ 3.60
Loan Agreement [Member]
Debt discount			$ 470	281
Loan Agreement [Member] \| Life Sciences Alternative Funding LLC [Member]
Principal amount of loan		$ 10,000
Loans bear interest		12.50%
Loans bear interest rate description		The term loan bore interest at a fixed per-annum rate of 12.5% and allowed for 2% of the interest to be paid-in-kind until December 2016. The Company was permitted to pay interest only until June 1, 2017.
Loan installments		20 months
Percentage of loan agreement final fee		5.00%
Loan due date		Jan. 01, 2019
Incurred expense debt		$ 1,066
Liability of final fee included in accrued expenses			667	$ 500
Issuance of warrants to purchase maximum number of shares		125,000
Common stock exercise price per share		$ 7.85
Issuance of warrants to purchase of common stock expiration year		10 years
Fair value of warrants		$ 840
Fair value of common stock		$ 7.97
Fair value of contractual term		10 years
Common stock volatility rate		109.00%
Fair value of dividend rate		0.00%
Fair value of risk-free interest rate		1.25%
Note Purchase Agreement [Member] \| Lender [Member] \| 8.00% Convertible Senior Secured Note [Member]
Loans bear interest	8.00%
Loan due date	May 11, 2021
Incurred expense debt	$ 228
Debt discount			534
Convertible note principal amount	$ 3,000
Convertible note fixed per annum rate	8.00%
Convertible note description	The Company is permitted to redeem the Convertible Note prior to its maturity at any time on or after March 1, 2018 for cash purchase prices equal to 109% - 105% of the outstanding principal amount of the Convertible Note, depending on the date of redemption.
Debt conversion price per share	$ 5.90
Proceeds from convertible note	$ 3,000
Percentage of repurchase convertible note in cash is greater than outstanding principal amount	105.00%
Fair value of embedded conversion feature	$ 2,322
Exchange Agreement [Member] \| Lender [Member]
Principal amount of loan					$ 3,000
Debt discount			$ 1,966
Convertible note principal amount					$ 13,332
Warrants exercise price per share			$ 1.79

Debt - Summary of Notes Payable (Details) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Less: Discounts on notes	$ (277)
Less: Current portion	3,973
Long-term portion	7,937	$ 8,336
Notes Payable [Member]
December 2016 Amended Note	13,332
Less: Discounts on notes	(1,422)
Less: Current portion	(4,999)
Long-term portion	$ 6,911

Debt - Summary of Future Minimum Payments (Details) $ in Thousands	Dec. 31, 2016 USD ($)
Less: unamortized discount	$ (277)
Notes Payable [Member]
2017	6,485
2018	8,905
Total minimum payments	15,390
Less: amount representing interest	(2,058)
Notes payable, gross	13,332
Less: unamortized discount	(1,422)
Note payable, net of unamortized debt discount	$ 11,910

Capital Lease Obligation (Details Narrative) - USD ($)		12 Months Ended
Capital Lease Obligation (Details Narrative) - USD ($)	Aug. 09, 2016	Dec. 31, 2016	Dec. 31, 2015
Property and equipment purchase price		$ (6,887,000)	$ (995,000)
Amortization of debt discount		970,000	281,000
Capital leases of equipment		2,070,000	60,000
Capital leases of accumulated depreciation		293,000	$ 9,000
Lease Agreement [Member]
Property and equipment purchase price	$ 2,000,000	2,000,000
Lease monthly payments	$ 64,000
Lease future payment		300,000
Lease incurred expenses		$ 67,000
Capital lease future minimum payments percentage		16.80%
Amortization of debt discount		$ 90,000

Capital Lease Obligation - Schedule of Future Payment Under Capital Lease (Details) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Leases [Abstract]
2017	$ 773
2018	773
2019	751
Total minimum lease payments	2,298
Less: amount representing interest payments	(244)
Present value of future minimum lease payments	2,053
Less: unamortized discount	(277)
Present value of future net minimum lease payments	1,776
Less: current portion, net of unamortized discount	(458)	$ (21)
Capital lease obligation, net of current portion and unamortized discount	$ 1,318	$ 1

Stockholders' Equity (Deficit) and Stock-Based Compensation (Details Narrative) - USD ($) $ / shares in Units, $ in Thousands		1 Months Ended									3 Months Ended	12 Months Ended
	Mar. 16, 2016	Dec. 31, 2016	Oct. 31, 2016	May 31, 2016	Mar. 31, 2016	Nov. 30, 2015	Jul. 31, 2015	Apr. 30, 2015	Feb. 28, 2015	Jan. 31, 2015	Dec. 31, 2015	Dec. 31, 2016	Dec. 31, 2015	Sep. 17, 2007
Common stock, shares authorized		90,000,000									90,000,000	90,000,000	90,000,000
Common stock, par value		$ 0.001									$ 0.001	$ 0.001	$ 0.001
Shares issued upon exercise of stock options, shares													130,457
Warrants exercise price per share	$ 3.60	$ 1.915										$ 1.915
Proceeds from offering price												$ 11,088
Number of shars issued for acquistion													425
Shares issued upon exercise of stock options												$ 55
Preferred stock, shares authorized		5,000,000									5,000,000	5,000,000	5,000,000
Preferred stock, par value		$ 0.001									$ 0.001	$ 0.001	$ 0.001
Preferred stock, shares issued		0									0	0	0
Preferred stock, shares outstanding		0									0	0	0
Fair value of option												$ 23	$ 39
Stock-based compensation												$ 3,673	$ 3,441
2007 Incentive Stock and Awards Plan [Member]
Number of shares available for sales		815,159										815,159
Maximum number of common stock issuance under the plan														5,000,000
Stock Option One [Member]
Shares issued upon exercise of stock options, shares												15,000
Number of common stock issued for warrant exercises												15,000
Sale of stock price per share		$ 3.68										$ 3.68
Shares issued upon exercise of stock options												$ 55
Investor Warrants [Member]
Proceeds from issuance of warrants		$ 9,217
Warrants exercise price per share		$ 1.79										$ 1.79
Percentage of cash commission		7.50%
Sales commission and offering expenses		$ 852
Sale of stock price per share		$ 1.915										$ 1.915
Agent Warrant [Member]
Number of warrants issued for purchase of common stock		210,313										210,313
Directors [Member]
Issuance of restricted common stock, shares												28,606
Non Employee Director [Member]
Issuance of restricted common stock, shares												63,450	34,166
Issuance of restricted common stock												$ 250	$ 270
Mark L. Baum [Member]
Issuance of restricted common stock, shares								157,500
Number of restricted stock forfeit during period								1,050,000
Mark Baum [Member] \| Baum Performance Option [Member]
Stock options to purchase shares of common stock							600,000
Stock option purchase of exercise price							$ 7.87
Fair value of option							$ 2,784
Option term							5 years
Volatility percentage							80.00%
Risk free interest rate							154.00%
Andrew R. Boll [Member]
Issuance of restricted common stock, shares									30,000
John P Saharek [Member]
Issuance of restricted common stock, shares									30,000
Issuance of restricted common stock									$ 442
Mr. Boll [Member]
Issuance of restricted common stock, shares									157,500
Park [Member]
Issuance of restricted common stock, shares										63,525
Issuance of restricted common stock										$ 425
PC [Member]
Number of shars issued for acquistion				$ 75,000
Number of shars issued for acquistion, shares				302
Sales Agreement [Member]
Percentage of cash commission						3.00%
Sales commission and offering expenses						$ 50					$ 16
Number of shares sold under the agreement											72,421
Proceeds from sale of common stock approximately											$ 529
Offerign expenses											$ 109
Offering expenses description											After deducting $16 in commission fees and $109 in offering expenses payable by the Company, of approximately $404.
Underwriting Agreement [Member]
Sales commission and offering expenses												$ 20
Number of shares sold under the agreement					3,335,000							57,042
Proceeds from sale of common stock approximately												$ 212
Sale of stock price per share					$ 3.60
Proceeds from offering price	$ 11,088
Number of shares available for sales		1,871										1,871
Securities Purchase Agreement [Member]
Number of shares sold under the agreement		5,257,828
Warrant One [Member]
Number of common stock issued for warrant exercises													220,912
Proceeds from issuance of warrants													$ 1,248
Warrant Two [Member]
Common stock issued upon warrants													209,980
Warrants exercise price per share											$ 5.925		$ 5.925
Warrant Three [Member]
Warrants exercise price per share											$ 5.25		$ 5.25
Number of common stock isused upon cashless exercise provisions of warrants													10,932
Number of warrants issued for purchase of common stock											30,457		30,457
Restricted Stock Units [Member]
Shares issued upon exercise of stock options, shares										8,521
Number of restricted stock issued													1,611
Number of shares vested during the period												80,245	55,824
Payroll tax withholdings													$ 10
Restricted Stock Units [Member] \| Employees [Member]
Number of shares vested during the period													1,241
Restricted Stock Units [Member] \| Directors [Member]
Number of shares vested during the period												24,421
Restricted Stock Units [Member] \| Non Employee Director [Member]
Number of shares vested during the period			16,076
Restricted Stock Units [Member] \| Mark L. Baum [Member]
Number of restricted stock issued												83,709
Number of shares vested during the period												200,000
Payroll tax withholdings												$ 144
Number of common stock shares issued for offering												116,291
Stock Option Plan [Member]
Shares issued upon exercise of stock options, shares												(15,000)
Stock option purchase of exercise price												$ 3.99
Intrinsic value of stock option exercised												$ 29
Closing price of common stock price per share		$ 2.50										$ 2.50
Stock options granted with exercise price contractual terms												5 years 9 months
Stock options granted vesting terms												Vesting terms for options granted in 2016 and 2015 to employees, directors and consultants typically included one of the following vesting schedules: 25% of the shares subject to the option vest and become exercisable on the first anniversary of the grant date and the remaining 75% of the shares subject to the option vest and become exercisable quarterly in equal installments thereafter over three years; quarterly vesting over three years; or 100% vesting associated with the provision or completion of services provided under contracts with consultants. Certain option awards provide for accelerated vesting if there is a change in control (as defined in the Plan) and in the event of certain modifications to the option award agreement.
Unrecognized compensation expense related to unvested stock options granted under the Plan		$ 5,116										$ 5,116
Stock-based compensation												$ 2,159	$ 1,747
Expense expected to recognize over the weighted-average remaining vesting period												3 years 1 month 6 days
Boll Performance Equity Award [Member]
Fair value of option												$ 228
Option term												3 years
Volatility percentage												60.00%
Risk free interest rate												0.77%
Unvested RSUs [Member]
Unrecognized compensation expense related to unvested stock options granted under the Plan		$ 3,873										$ 3,873
Stock-based compensation												$ 1,539	$ 1,671
Expense expected to recognize over the weighted-average remaining vesting period												1 year 9 months 18 days
Minimum [Member]
Stock options to purchase shares of common stock													255,600
Stock option purchase of exercise price													$ 3.20
Minimum [Member] \| Mark L. Baum [Member]
Average stock price targets ranging								$ 9
Minimum [Member] \| Mark Baum [Member] \| Baum Performance Option [Member]
Average stock price targets ranging							$ 9
Minimum [Member] \| Stock Option Plan [Member]
Stock options granted with exercise price contractual terms												5 years
Minimum [Member] \| Boll Performance Equity Award [Member]
Average stock price targets ranging												$ 10
Maximum [Member]
Stock option purchase of exercise price													$ 4.51
Maximum [Member] \| Mark L. Baum [Member]
Average stock price targets ranging								$ 15
Maximum [Member] \| Mark Baum [Member] \| Baum Performance Option [Member]
Average stock price targets ranging							$ 15
Maximum [Member] \| Stock Option Plan [Member]
Stock options granted with exercise price contractual terms												10 years
Maximum [Member] \| Boll Performance Equity Award [Member]
Average stock price targets ranging												$ 30

Stockholders' Equity (Deficit) and Stock-Based Compensation - Schedule of Stock Option Plan Activity (Details) - USD ($) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015
Number of shares, Options exercised		130,457
Weighted Avg. Exercise Price, Exercisable Ending Balance	$ 6.20
Stock Option Plan [Member]
Number of shares, Outstanding, Beginning balance	1,544,026
Number of shares, Options granted	549,350
Number of shares, Options exercised	(15,000)
Number of shares, Options cancelled/forfeit	(65,063)
Number of shares, Outstanding, Ending balance	2,013,313	1,544,026
Number of shares, Options exercisable	808,067
Number of shares, Options vested and expected to vest	1,892,790
Weighted Avg. Exercise Price, Outstanding, Beginning balance	$ 5.74
Weighted Avg. Exercise Price, Options granted	3.99
Weighted Avg. Exercise Price, Options exercised	3.68
Weighted Avg. Exercise Price, Options cancelled/forfeit	7.80
Weighted Avg. Exercise Price, Outstanding, Ending balance	6.20	$ 5.74
Weighted Avg. Exercise Price, Exercisable Ending Balance	6.18
Weighted Avg. Exercise Price, Vested and expected to vest	$ 6.20
Weighted Avg. Remaining Contractual Life, Options outstanding	6 years 3 months 11 days
Weighted Avg. Remaining Contractual Life, Options exercisable	5 years 9 months
Weighted Avg. Remaining Contractual Life, Options vested and expected to vest	6 years 1 month 6 days
Aggregate Intrinsic Value, Options outstanding	$ 13
Aggregate Intrinsic Value, Options exercisable	13
Aggregate Intrinsic Value, Options vested and expected to vest	$ 13

Stockholders' Equity (Deficit) and Stock-Based Compensation - Schedule of Market-based Vesting Conditions for Stock Option Units Granted (Details)	12 Months Ended
	Dec. 31, 2016 shares
Tranche 1 [Member]
Number of shares vesting	200,000
Target share price description	9.00 or greater
Tranche 2 [Member]
Number of shares vesting	100,000
Target share price description	10.00 or greater
Tranche 3 [Member]
Number of shares vesting	100,000
Target share price description	12.00 or greater
Tranche 4 [Member]
Number of shares vesting	100,000
Target share price description	14.00 or greater
Tranche 5 [Member]
Number of shares vesting	100,000
Target share price description	15.00 or greater

Stockholders' Equity (Deficit) and Stock-Based Compensation - Schedule of Fair Value Assumption (Details) - $ / shares	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015
Options Granted to Employees [Member]
Weighted-average fair value of granted	$ 3.91	$ 6.22
Expected volatility, minimum	101.00%	101.00%
Expected volatility, maximum	112.00%	121.00%
Risk-free interest rate, minimum	1.07%	1.39%
Risk-free interest rate, maximum	1.70%	1.68%
Dividend yield
Options Granted to Employees [Member] \| Minimum [Member]
Expected terms (in years)	5 years 9 months 22 days	5 years 9 months 22 days
Options Granted to Employees [Member] \| Maximum [Member]
Expected terms (in years)	6 years 1 month 10 days	6 years 1 month 10 days
Options Granted to Consultants [Member]
Weighted-average fair value of granted	$ 6.18	$ 6.49
Expected terms (in years)	10 years	10 years
Expected volatility	109.00%
Expected volatility, minimum		108.00%
Expected volatility, maximum		109.00%
Risk-free interest rate	1.06%
Risk-free interest rate, minimum		1.06%
Risk-free interest rate, maximum		1.63%
Dividend yield
Warrant Granted [Member]
Weighted-average fair value of granted	$ 2.88
Expected terms (in years)	5 years
Expected volatility	106.00%
Risk-free interest rate	0.79%
Dividend yield

Stockholders' Equity (Deficit) and Stock-Based Compensation - Schedule of Shares Outstanding and Exercisable (Details)	12 Months Ended
	Dec. 31, 2016 $ / shares shares
Number of Options Outstanding \| shares	2,013,313
Weighted Average Remaining Contractual Life in Years	6 years 3 months 11 days
Weighted Average Exercise Price	$ 6.20
Number Exercisable \| shares	808,067
Weighted Average Exercisable Exercise Price	$ 6.18
Range One [Member]
Range of Exercise Prices, minimum	2.40
Range of Exercise Prices, maximum	$ 2.60
Number of Options Outstanding \| shares	147,000
Weighted Average Remaining Contractual Life in Years	5 years 9 months 18 days
Weighted Average Exercise Price	$ 2.43
Number Exercisable \| shares	125,000
Weighted Average Exercisable Exercise Price	$ 2.40
Range Two [Member]
Range of Exercise Prices, minimum	3.74
Range of Exercise Prices, maximum	$ 4.50
Number of Options Outstanding \| shares	695,623
Weighted Average Remaining Contractual Life in Years	7 years 8 months 9 days
Weighted Average Exercise Price	$ 4.05
Number Exercisable \| shares	225,256
Weighted Average Exercisable Exercise Price	$ 4.25
Range Three [Member]
Range of Exercise Prices, minimum	5.49
Range of Exercise Prices, maximum	$ 7.99
Number of Options Outstanding \| shares	952,103
Weighted Average Remaining Contractual Life in Years	5 years 4 days
Weighted Average Exercise Price	$ 7.54
Number Exercisable \| shares	249,857
Weighted Average Exercisable Exercise Price	$ 6.83
Range Four [Member]
Range of Exercise Prices, minimum	8.06
Range of Exercise Prices, maximum	$ 8.99
Number of Options Outstanding \| shares	213,557
Weighted Average Remaining Contractual Life in Years	6 years 1 month 6 days
Weighted Average Exercise Price	$ 8.92
Number Exercisable \| shares	202,924
Weighted Average Exercisable Exercise Price	$ 8.95
Range Five [Member]
Range of Exercise Prices, minimum	$ 42.80
Number of Options Outstanding \| shares	5,030
Weighted Average Remaining Contractual Life in Years	3 years 10 months 13 days
Weighted Average Exercise Price	$ 42.80
Number Exercisable \| shares	5,030
Weighted Average Exercisable Exercise Price	$ 42.80

Stockholders' Equity (Deficit) and Stock-Based Compensation - Schedule of Market-based Vesting Conditions for Restricted Stock Units Granted (Details)	12 Months Ended
	Dec. 31, 2016 shares
Tranche 1 [Member]
Number of shares vesting	200,000
Target share price description	9.00 or greater
Tranche 2 [Member]
Number of shares vesting	100,000
Target share price description	10.00 or greater
Tranche 3 [Member]
Number of shares vesting	100,000
Target share price description	12.00 or greater
Tranche 4 [Member]
Number of shares vesting	100,000
Target share price description	14.00 or greater
Tranche 5 [Member]
Number of shares vesting	100,000
Target share price description	15.00 or greater
Restricted Stock Units [Member] \| Tranche 1 [Member]
Number of shares vesting	30,000
Target share price description	10.00 or greater
Restricted Stock Units [Member] \| Tranche 2 [Member]
Number of shares vesting	30,000
Target share price description	15.00 or greater
Restricted Stock Units [Member] \| Tranche 3 [Member]
Number of shares vesting	30,000
Target share price description	20.00 or greater
Restricted Stock Units [Member] \| Tranche 4 [Member]
Number of shares vesting	30,000
Target share price description	25.00 or greater
Restricted Stock Units [Member] \| Tranche 5 [Member]
Number of shares vesting	37,500
Target share price description	30.00 or greater
Accelerated [Member] \| Tranche 1 [Member]
Number of shares vesting	230,000
Target share price description	9.00 or greater
Accelerated [Member] \| Tranche 2 [Member]
Number of shares vesting	230,000
Target share price description	10.00 or greater
Accelerated [Member] \| Tranche 3 [Member]
Number of shares vesting	230,000
Target share price description	12.00 or greater
Accelerated [Member] \| Tranche 4 [Member]
Number of shares vesting	230,000
Target share price description	14.00 or greater
Accelerated [Member] \| Tranche 5 [Member]
Number of shares vesting	287,500
Target share price description	15.00 or greater

Stockholders' Equity (Deficit) and Stock-Based Compensation - Schedule of Assumptions Used (Details)	12 Months Ended
	Dec. 31, 2016 $ / shares
Equity [Abstract]
Market price	$ 3.98
Contractual terms (in years)	5 years
Expected volatility	102.00%
Risk-free interest rate	1.04%
Dividend yield

Stockholders' Equity (Deficit) and Stock-Based Compensation - Schedule of Restricted Stock Units Activity (Details) - Restricted Stock Units [Member]	12 Months Ended
	Dec. 31, 2016 $ / shares shares
Number of RSUs unvested, Outstanding, Beginning balance \| shares	1,487,961
Number of RSUs granted \| shares	1,270,950
Number of RSUs vested \| shares	(249,018)
Number RSUs cancelled/forfeit \| shares	(1,217,017)
Number of RSUs unvested, Outstanding, Ending balance \| shares	1,292,876
Weighted Average Grant Date Fair Value, Beginning balance \| $ / shares	$ 3.18
Weighted Average Grant Date Fair Value, RSUs granted \| $ / shares	2.25
Weighted Average Grant Date Fair Value, RSUs vested \| $ / shares	8.32
Weighted Average Grant Date Fair Value, RSUs cancelled/forfeit \| $ / shares	1.95
Weighted Average Grant Date Fair Value, Ending balance \| $ / shares	$ 2.43

Stockholders' Equity (Deficit) and Stock-Based Compensation - Schedule of Stock Based Compensation Granted to Employees Directors Consultants (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015
Stock based compensation related to equity instruments granted to related parties	$ 3,788	$ 3,441
Employees [Member] \| Selling and Marketing [Member]
Stock based compensation related to equity instruments granted to related parties	498	370
Employees [Member] \| General and Administrative [Member]
Stock based compensation related to equity instruments granted to related parties	2,954	2,720
Directors [Member] \| General and Administrative [Member]
Stock based compensation related to equity instruments granted to related parties	221	268
Consultants [Member] \| Selling and Marketing [Member]
Stock based compensation related to equity instruments granted to related parties		83
Other [Member] \| General and Administrative [Member]
Stock based compensation related to equity instruments granted to related parties	$ 115

Stockholders' Equity (Deficit) and Stock-Based Compensation - Schedule of Warrants Activity (Details) - Warrant [Member]	12 Months Ended
	Dec. 31, 2016 $ / shares shares
Number of shares, outstanding, beginning balance \| shares	240,688
Number of shares subject to warrants outstanding, granted \| shares	5,508,141
Number of shares subject to warrants outstanding, exercised \| shares
Number of shares subject to warrants outstanding, expired \| shares
Number of shares, outstanding, ending balance \| shares	5,748,829
Weighted average remaining contractual life of the outstanding warrants in years	3 years 29 days
Weighted avg. Exercise price, outstanding, beginning balance \| $ / shares	$ 7.41
Weighted avg. Exercise price, granted \| $ / shares	1.80
Weighted avg. Exercise price, exercised \| $ / shares
Weighted avg. Exercise price, expired/forfeited \| $ / shares
Weighted avg. Exercise price, outstanding, ending balance \| $ / shares	$ 1.91

Stockholders' Equity (Deficit) and Stock-Based Compensation - Schedule of Warrants Outstanding and Warrants Exercisable (Details) - $ / shares	12 Months Ended
	Dec. 31, 2016	Mar. 16, 2016
Exercise Price	$ 1.915	$ 3.60
Expiration Date	May 11, 2025
Warrant [Member]
Warrants Outstanding	5,748,829
Exercise Price	$ 1.91
Warrants Exercisable	280,688
Lender Warrants [Member]
Issue Date	May 11, 2015
Warrants Outstanding	125,000
Exercise Price	$ 1.79
Warrants Exercisable	125,000
Expiration Date	May 11, 2025
Underwriter Warrants [Member]
Issue Date	Feb. 07, 2013
Warrants Outstanding	55,688
Exercise Price	$ 5.25
Warrants Exercisable	55,688
Expiration Date	Feb. 07, 2018
Settlement Warrants [Member]
Issue Date	Aug. 16, 2016
Warrants Outstanding	40,000
Exercise Price	$ 3.75
Warrants Exercisable	40,000
Expiration Date	Aug. 16, 2021
Warrants Issued to Investor Relations Consultant [Member]
Issue Date	Jul. 19, 2013
Warrants Outstanding	60,000
Exercise Price	$ 8.50
Warrants Exercisable	60,000
Expiration Date	Jul. 19, 2018
Placement Agent Warrants [Member]
Issue Date	Dec. 27, 2016
Warrants Outstanding	210,313
Exercise Price	$ 1.79
Warrants Exercisable
Expiration Date	Dec. 27, 2019
PIPE Investor Warrants [Member]
Issue Date	Dec. 27, 2016
Warrants Outstanding	5,257,828
Exercise Price	$ 1.79
Warrants Exercisable
Expiration Date	Dec. 27, 2019

Derivative Instruments (Details Narrative) - $ / shares	12 Months Ended
Derivative Instruments (Details Narrative) - $ / shares	Dec. 31, 2016	Mar. 16, 2016
Derivative Instruments and Hedging Activities Disclosure [Abstract]
Debt conversion price per share	$ 5.90	$ 5.90
Warrants exercise price per share	$ 1.915	$ 3.60
Warrants expiration date	May 11, 2025
Convertible note original maturity date	May 11, 2021

Derivative Instruments - Schedule of Derivative Liabilities at Fair Value (Details)	12 Months Ended
	Dec. 31, 2016
Expected volatility	102.00%
Risk-free interest rate	1.04%
Dividend yield
Minimum [Member]
Expected volatility	103.00%
Risk-free interest rate	1.22%
Maximum [Member]
Expected volatility	111.00%
Risk-free interest rate	1.70%

Derivative Instruments - Fair Value at Reconciliation of Measured Liabilities (Details) $ in Thousands	12 Months Ended
	Dec. 31, 2016 USD ($)
Warrant Derivative Liability [Member]
Balance Beginning
Modification of warrant and reclassification from equity to liabilities	675
Change in fair value	(211)
Reclassification from liabilities to equity upon closing of public equity offering	(464)
Balance Ending
Embedded Conversion Feature Derivative Liability [Member]
Balance Beginning
Embedded conversion feature in Convertible Note issued	2,322
Change in fair value	324
Reclassification from liabilities to equity upon closing of public equity offering	(2,646)
Balance Ending

Income Taxes (Details Narrative) - USD ($) $ in Thousands	12 Months Ended
Income Taxes (Details Narrative) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Income Taxes Details Narrative
Deferred tax asset valuation allowance	$ 7,400	$ 5,200
Federal net operating loss carryforwards	$ 54,275
Federal net operating loss expiration date	2027
Federal research and development tax credits	$ 354
Federal research and development tax credits expiration date	2026
State net operating loss carryforwards		52,334
State net operating loss expiration date	2017
State research and development tax credits	$ 305
Unrecognized tax benefits

Income Taxes - Schedule of Provision for Income Taxes (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015
Income Tax Disclosure [Abstract]
Current: Federal
Current: State	8	5
Total current	8	5
Deferred: Federal	19,847	14,037
Deferred: State	5,802	4,036
Deferred: Change in valuation allowance	(25,760)	(18,072)
Total deferred	(111)
Income tax provision (benefit)	$ 111

Income Taxes - Schedule of Income Tax Reconciliation (Details)	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015
Income Tax Disclosure [Abstract]
U.S. federal statutory tax rate	35.00%	35.00%
Benefit of lower tax brackets	(1.00%)	(1.00%)
State tax benefit, net	0.08%	(0.03%)
Research and development credits	0.00%	0.00%
Employee stock based compensation	(1.47%)	(0.67%)
Loss on debt conversion	0.00%	0.00%
Other	(0.18%)	(0.71%)
Valuation allowance	(31.89%)	(32.62%)
Effective income tax rate	0.54%	(0.03%)

Income Taxes - Schedule of Deferred Tax Assets and Liabilities (Details) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Income Tax Disclosure [Abstract]
NOL's	$ 21,536	$ 15,099
Depreciation and amortization	199	121
Other	398	346
Research & development credits	556	556
Deferred stock compensation	3,875	2,997
Park stock purchase identifiable intangibles	(936)	(1,047)
Unrealized gain or loss on investments
Total deferred tax assets, net	25,647	18,072
Valuation allowance	(26,583)	(19,119)
Net deferred tax liabilities	$ (936)	$ (1,047)

Employee Savings Plan (Details Narrative) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015
Compensation and Retirement Disclosure [Abstract]
Percentage of salary deposits in tax deferred investment account	100.00%
Percentage of contributions made by the company	4.00%
Contributions by the company	$ 248	$ 146

Commitments and Contingencies (Details Narrative) $ in Thousands				1 Months Ended					12 Months Ended
	May 31, 2016 USD ($) shares	Sep. 02, 2014 USD ($)	Apr. 02, 2014 USD ($) shares	Aug. 31, 2016 USD ($)	Aug. 31, 2015 USD ($) ft²	Feb. 28, 2015 USD ($) ft²	Jan. 31, 2015 USD ($) ft²	Jun. 30, 2014 ft²	Dec. 31, 2016 USD ($)	Dec. 31, 2015 USD ($)	Apr. 30, 2016 USD ($)	Sep. 30, 2014 ft²
Fair value of contingent acquisition obligation										$ 483
Issuance of common stock to settle contingent acquisition obligation									$ 302
Gain loss on contingent acquisition									81
Lease agreement for office space (Square feet) \| ft²												7,565
Operating lease, monthly rental									668	641
Gain on settlement				$ 40,000					551
Insurance claim in other income									861
Accrued royalty expenses									3	$ 0
License Agreement [Member]
Lease agreement for office space (Square feet) \| ft²						8,602
Operating lease Expiry						Jul. 31, 2022
Operating lease, monthly rental						$ 10
Operating lease, rent increase percentage						3.75%
License Agreement [Member] \| Urigen Pharmaceuticals, Inc [Member]
Unpaid royalties											$ 698
Lease Agreements [Member]
Lease agreement for office space (Square feet) \| ft²					1,100		4,500	7,565
Operating lease Expiry					Oct. 31, 2019		Dec. 31, 2020	Oct. 31, 2018
Operating lease, monthly rental		$ 20,426			$ 3		$ 10
Operating lease, rent increase percentage		3.00%			2.00%		3.00%
Pharmacy Creations, LLC [Member]
Fair value of divided ratio			18.5882
Number of common stock shares issued for maximum exceeds from revenue \| shares	75,000		215,190
Payment of cash	$ 100
Pharmacy Creations, LLC [Member] \| Minimum [Member]
Revenue									3,500
Number of common stock shares issued for exceeds revenue value			$ 3,500
Pharmacy Creations, LLC [Member] \| Maximum [Member]
Revenue									$ 7,500

Commitments and Contingencies - Schedule of Future Payments Under Leases (Details) $ in Thousands	Dec. 31, 2016 USD ($)
Compensation and Retirement Disclosure [Abstract]
2017	$ 495
2018	496
2019	257
2020	266
2021	134
Thereafter	79
Total	$ 1,727

Segment Information and Concentrations (Details Narrative)	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015
Segment Reporting [Abstract]
Maximum percentage of sales derived from single customer	10.00%	10.00%
Percentage of drug and chemical purchases from three main suppliers	63.00%	43.00%

Subsequent Events (Details Narrative) - Subsequent Event [Member] $ in Thousands	1 Months Ended
	Feb. 28, 2017 USD ($)
Imprimis TX [Member]
Percentage of issued and outstanding shares of common stock	100.00%
Livernois [Member]
Purchase consideration value	$ 10
Remaining lease obligation amount	$ 113